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Fertility

Genetics has a great deal to say about the timing of reproduction across populations and almost nothing to say to one person trying to conceive.

Why this topic Birth rates are a headline in a dozen countries at once, egg freezing has become ordinary, and IVF is discussed in the open by people who would not have mentioned it a decade ago.

What this topic connects to

Fertility Variant: rs1801133 rs1801133 Variant Variant: rs995030 rs995030 Variant Variant: rs1801131 rs1801131 Variant Variant: rs10941679 rs10941679 Variant Variant: rs13429458 rs13429458 Variant Variant: +44 more +44 more Variant Fertility Fertility

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

Variants that share a paper with this

Counted in Europe PMC, where the title or abstract names both this topic and that rsID. The number is papers, not evidence of a cause.

rs1801133

MTHFR

Folate metabolism (MTHFR C677T)

11 papers →

rs995030

KITLG

Testicular germ cell tumor

6 papers →

rs1801131

MTHFR

Folate metabolism (MTHFR A1298C)

5 papers →

rs10941679

near MRPS30

Breast cancer

3 papers →

rs13429458

ZFP36L2

Polycystic ovary syndrome

3 papers →

rs16991615

MCM8

Menopause (age at onset)

3 papers →

rs1799964

HLA-DQA2

Crohn's disease

3 papers →

rs3817198

LSP1

Breast cancer

3 papers →

rs11889341

STAT4

Systemic lupus erythematosus

2 papers →

rs12478601

ZFP36L2

Polycystic ovary syndrome

2 papers →

rs13394619

GREB1

Endometriosis

2 papers →

rs1537377

CDKN2B-ASI

Endometriosis

2 papers →

rs2153157

SYCP2L

Menopause (age at onset)

2 papers →

rs4149056

SLCO1B1

Statin muscle-side-effect risk

2 papers →

rs4973768

SLC4A7

Breast cancer

2 papers →

rs6504950

COX11

Breast cancer

2 papers →

rs7582694

STAT4

Type 1 diabetes

2 papers →

rs10069690

TERT

Breast cancer

1 paper →

rs10246939

TAS2R38

Bitter taste perception (TAS2R38 position 296)

1 paper →

rs1046089

PRRC2A

Menopause (age at onset)

1 paper →

rs10818854

DENND1A

Polycystic ovary syndrome

1 paper →

rs10846744

SCARB1

Lipoprotein-associated phospholipase A2 activity and mass

1 paper →

rs10995190

ZNF365

Breast cancer

1 paper →

rs11209026

IL23R

Crohn's disease

1 paper →

rs1122608

LDLR

Myocardial infarction (early onset)

1 paper →

rs11571833

BRCA2

Cancer

1 paper →

rs1172822

BRSK1

Menarche and menopause (age at onset)

1 paper →

rs12150660

SHBG

Testosterone levels

1 paper →

rs1229984

ADH1B

Alcohol metabolism speed

1 paper →

rs12970134

MC4R

Waist circumference and related phenotypes

1 paper →

rs1421085

FTO

Obesity

1 paper →

rs16890979

SLC2A9

Urate levels

1 paper →

rs1799969

ICAM1

Soluble ICAM-1

1 paper →

rs1800469

TGFB1

Colorectal cancer

1 paper →

rs1803274

BCHE

Cardiovascular disease risk factors

1 paper →

rs2046210

ESR1

Breast cancer

1 paper →

rs2727270

FTH1

Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)

1 paper →

rs2736100

TERT

Lung adenocarcinoma

1 paper →

rs333

CCR5

HIV-1 resistance (CCR5-delta32)

1 paper →

rs34536443

TYK2

Type 1 diabetes

1 paper →

rs4244285

CYP2C19

CYP2C19 *2 — clopidogrel activation

1 paper →

rs4343

ACE

Angiotensin-converting enzyme activity

1 paper →

rs4624820

SPRY4

Testicular germ cell tumor

1 paper →

rs5498

ICAM1

Soluble ICAM-1

1 paper →

rs6025

F5

Blood clotting risk (Factor V Leiden)

1 paper →

rs671

ALDH2

Alcohol flush reaction

1 paper →

rs7270101

ITPA

Chronic hepatitis C infection

1 paper →

rs780093

GCKR

Crohn's disease

1 paper →

rs8050136

FTO

Type 2 diabetes

1 paper →

How this was counted

Europe PMC, title and abstract only, searched for “age at first birth”, “infertility”, “ovarian reserve” alongside each published rsID. Full text was not counted: it returns every paper with an rsID buried in a supplementary table. Recounted monthly.