3 462234224225Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple4China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 3,181 European ancestry cases, 8,075 European ancestry controls, 1,423 Japanese ancestry cases, 1,318 Japanese ancestry controls; replicated in 1,044 Japanese ancestry, 4,017 Japanese ancestry controls.
The effect
Each copy of the C allele carried 1.15 times the odds of Endometriosis (95% confidence interval 1.10-1.21); p = 2 × 10−9.
How common The C allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 9, band 9p21.3 — in a regulatory region of CDKN2B-AS1.
What each result means
C/CTwo copies of the version the research linked to Endometriosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Endometriosis. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Endometriosis. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1537377
What is rs1537377?
rs1537377 is a single position in the genome, in or near the CDKN2B-ASI gene. Published research associates it with endometriosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1537377 linked to?
On MyGeneLog this position is linked to Endometriosis and Depression: Shared Genetics. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs1537377?
Subjects that appear in the title or abstract of the same papers as this rsID include fertility (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1537377 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1537377 come from?
GWAS Catalog, Nat Genet 2012, PMID:23104006. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 462234224225Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity3Meta AI4Microsoft · Copilot2Amazon2Apple4China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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