BMP4 · rs17563
Where this position leads
Condition: Tooth Eruption Timing
What the study found
Who was studied 11,118 European ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.239 lower (95% confidence interval 0.18-0.3); p = 9 × 10−17.
Where it sits Chromosome 14, band 14q22.2 — a missense change in BMP4.
What ClinVar records
Classification
Benign/Likely benign for Orofacial cleft 11, Microphthalmia with brain and digit anomalies; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 13 submitters), last evaluated 2026-02-04.
ClinVar record 197190 NM_001202.6(BMP4):c.455T>C (p.Val152Ala)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs17563 is a single position in the genome, in or near the BMP4 gene. Published research associates it with primary tooth development (time to first tooth eruption). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Tooth Eruption Timing. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include alcohol and the flush (1 papers), bones and fractures (1 papers), fertility (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Hum Mol Genet 2013, PMID:23704328. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Primary tooth development (time to first tooth eruption) (rs17563). MyGeneLog™. https://www.mygenelog.com/variants/rs17563