Standard

Lipoprotein-associated phospholipase A2 activity and mass

SCARB1 · rs10846744

What the study found

Who was studied 6,668 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 4.6 nmol/ml/min higher; p = 1 × 10−8.

How common The C allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of SCARB1.

What each result means

C/C Two copies of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lipoprotein-associated phospholipase A2 activity and mass. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs10846744

What is rs10846744?

rs10846744 is a single position in the genome, in or near the SCARB1 gene. Published research associates it with lipoprotein-associated phospholipase a2 activity and mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs10846744?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (5 papers), infection and immunity (3 papers), cholesterol and blood fats (1 papers), fertility (1 papers), skin, sun and hair (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs10846744 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10846744 come from?

GWAS Catalog, PLoS Genet 2010, PMID:20442857. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lipoprotein-associated phospholipase A2 activity and mass (rs10846744). MyGeneLog™. https://www.mygenelog.com/variants/rs10846744

← See all variants