Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 385 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
Cancer of Other Male Genital Organs, as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 3,018 cases and 569,607 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → ConditionDyshidrosis, as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 2,455 cases and 626,220 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → MetabolicDiabetes (standard GWA), as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 283,227 individuals (European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionChondrocalcinosis, as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 3,282 cases and 625,577 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → DigestiveAcute Gastritis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 2,691 cases and 617,490 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → DigestiveDuodenitis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 2,938 cases and 619,683 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → UrologicalDysplasia of Prostate, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 1,376 cases and 518,488 controls (African American or Afro-Caribbean ancestry, European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → CancerCancer of Major Salivary Glands, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 1,130 cases and 571,603 controls (African American or Afro-Caribbean ancestry, European ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → HematologicPernicious Anemia, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 1,429 cases and 570,568 controls (African American or Afro-Caribbean ancestry, European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionComplex Regional/central Pain Syndrome, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 3,122 cases and 625,178 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → UrologicalGlomerulonephritis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 2,204 cases and 629,134 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → ConditionCostochondritis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 902 cases and 567,630 controls (African American or Afro-Caribbean ancestry, European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → ConditionSuperficial Keratitis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 2,528 cases and 623,139 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionPyogenic Granuloma, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 1,065 cases and 569,509 controls (African American or Afro-Caribbean ancestry, European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → MusculoskeletalIntervertebral Disc Disorder, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 58,854 cases and 922,958 controls (European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → CardiovascularTransthyretin amyloidosis (ATTR) is when a blood protein called transthyretin falls apart, misfolds and builds up in the heart or the nerves. It can be inherited through a typo in the TTR gene, or come with age in people whose gene is normal. Three medicines are now approved for the heart form.
Read more → EndocrineAutoimmune Addison's disease is the immune system's destruction of the adrenal cortex. The first genome-wide study of it found nine risk loci: immune genes it shares with other autoimmune diseases, and AIRE, a gene that teaches the immune system what not to attack.
Read more → DigestiveGallstones are hardened deposits that form in the gallbladder. A genome-wide meta-analysis of 43,639 cases and 506,798 controls found 75 risk loci and implicated genes that control how the gut and gallbladder move.
Read more → CardiovascularA heart muscle disease in which the main pumping chamber enlarges and contracts weakly, and a leading cause of heart failure. The largest study behind this page found 70 genome-wide significant loci and pointed to higher body weight and higher systolic blood pressure as potential causes.
Read more → ConditionRespiratory Insufficiency, as genome-wide studies have reported it: 6 positions from 1 study, the largest recording 2,918 cases and 624,478 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
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One diagnosed condition or measurable trait covered properly: what it actually is, what causes it, how common it is, how it is diagnosed, and the specific variants with a replicated link to it — every claim sourced from published research.
No. Every page here is informational, not a diagnosis. A result should be discussed with a doctor or a licensed genetic counselor, never acted on alone.
Because they are not disorders. Height, ABO blood group and a handful of others describe a measurable characteristic with nothing to diagnose — "Trait" says so plainly instead of implying a disease that is not one.
Only after a replicated association in published research, verified against the primary study rather than a gene name or a marketing claim — the same discipline the variant pages themselves follow.