Sensitive

Systemic lupus erythematosus

STAT4 · rs11889341

Where this position leads

Condition: Systemic Lupus Erythematosus

rs11889341 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs11889341 rs11889341 STAT4

What the study found

Who was studied 5,201 European ancestry cases, 9,066 European ancestry controls.

The effect Each copy of the T allele carried 1.68 times the odds of Systemic lupus erythematosus; p = 2 × 10−76.

Where it sits Chromosome 2, band 2q32.2 — in an intron of STAT4.

What each result means

C/C No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11889341

What is rs11889341?

rs11889341 is a single position in the genome, in or near the STAT4 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11889341 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs11889341?

Subjects that appear in the title or abstract of the same papers as this rsID include fertility (2 papers), infection and immunity (2 papers), liver (2 papers), blood sugar and insulin (1 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11889341 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11889341 come from?

GWAS Catalog, Nat Genet 2015, PMID:26502338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (rs11889341). MyGeneLog™. https://www.mygenelog.com/variants/rs11889341

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