Gene Knowledge Graph UTC
Sensitive

Colorectal cancer

TGFB1 · rs1800469

Where this position leads

Condition: Colorectal Cancer

rs1800469 Condition: Colorectal Cancer Colorectal Cancer Condition Topic: Infection and immunity Infection and immunity Topic Topic: Bones and fractures Bones and fractures Topic Topic: Kidneys Kidneys Topic rs1800469 rs1800469 TGFB1

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Colorectal cancer — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2014, PMID:24836286)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Colorectal cancer. (GWAS Catalog, Nat Genet 2014, PMID:24836286)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Colorectal cancer compared to the general population. (GWAS Catalog, Nat Genet 2014, PMID:24836286)

Source: GWAS Catalog, Nat Genet 2014, PMID:24836286

What people read about alongside this

Infection and immunity9 Bones and fractures5 Kidneys4 Short-sightedness and screens3 Fertility1 Allergies1 Liver1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs1800469

What is rs1800469?

rs1800469 is a single position in the genome, in or near the TGFB1 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1800469 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs1800469?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (9 papers), bones and fractures (5 papers), kidneys (4 papers), short-sightedness and screens (3 papers), fertility (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs1800469 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1800469 come from?

GWAS Catalog, Nat Genet 2014, PMID:24836286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants