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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 8,631 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.69 higher (95% confidence interval 0.55-0.83); p = 3 × 10−21.
How common The T allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 11, band 11q12.2 — in an intron of FADS2.
What each result means
C/CNo copy of the version the research linked to Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs2727270
What is rs2727270?
rs2727270 is a single position in the genome, in or near the FTH1 gene. Published research associates it with plasma omega-6 polyunsaturated fatty acid levels (linoleic acid). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs2727270?
Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (3 papers), blood sugar and insulin (1 papers), heart and circulation (1 papers), alcohol and the flush (1 papers), fertility (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs2727270 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2727270 come from?
GWAS Catalog, Circ Cardiovasc Genet 2014, PMID:24823311. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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