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Endometriosis

GREB1 · rs13394619

Where this position leads

Condition: Endometriosis and Depression: Shared Genetics

rs13394619 Condition: Endometriosis and Depression: Shared Genetics Endometriosis and Depression: Share… Condition rs13394619 rs13394619 GREB1

What the study found

Who was studied 3,181 European ancestry cases, 8,075 European ancestry controls, 1,423 Japanese ancestry cases, 1,318 Japanese ancestry controls; replicated in 1,044 Japanese ancestry, 4,017 Japanese ancestry controls.

The effect Each copy of the G allele carried 1.15 times the odds of Endometriosis (95% confidence interval 1.09-1.20); p = 6 × 10−9.

How common The G allele had a frequency of about 52% in the people studied.

Where it sits Chromosome 2, band 2p25.1 — in an intron of GREB1.

What each result means

A/A No copy of the version the research linked to Endometriosis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Endometriosis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Endometriosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs13394619

What is rs13394619?

rs13394619 is a single position in the genome, in or near the GREB1 gene. Published research associates it with endometriosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13394619 linked to?

On MyGeneLog this position is linked to Endometriosis and Depression: Shared Genetics. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs13394619?

Subjects that appear in the title or abstract of the same papers as this rsID include fertility (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs13394619 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13394619 come from?

GWAS Catalog, Nat Genet 2012, PMID:23104006. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Endometriosis (rs13394619). MyGeneLog™. https://www.mygenelog.com/variants/rs13394619

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