Standard

Menopause (age at onset)

SYCP2L · rs2153157

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Menopause (age at onset) compared to the general population. (GWAS Catalog, Nat Genet 2012, PMID:22267201)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Menopause (age at onset). (GWAS Catalog, Nat Genet 2012, PMID:22267201)

G/G Published research associates this genotype with typical/baseline likelihood of Menopause (age at onset) — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2012, PMID:22267201)

Source: GWAS Catalog, Nat Genet 2012, PMID:22267201

Questions about rs2153157

What is rs2153157?

rs2153157 is a single position in the genome, in or near the SYCP2L gene. Published research associates it with menopause (age at onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2153157 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2153157 come from?

GWAS Catalog, Nat Genet 2012, PMID:22267201. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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