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Testosterone levels

SHBG · rs12150660

What the study found

Who was studied 8,938 European ancestry male individuals; replicated in 5,491 European ancestry male individuals.

The effect Each copy of the T allele shifted the measure 31.8 ng/dl higher (95% confidence interval 27.29-36.31); p = 1 × 10−41.

How common The T allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in an intron of SHBG.

What each result means

G/G No copy of the version the research linked to Testosterone levels. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Testosterone levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs12150660

What is rs12150660?

rs12150660 is a single position in the genome, in or near the SHBG gene. Published research associates it with testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs12150660?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers), bones and fractures (1 papers), cholesterol and blood fats (1 papers), exercise and muscle (1 papers), fertility (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs12150660 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12150660 come from?

GWAS Catalog, PLoS Genet 2011, PMID:21998597. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Testosterone levels (rs12150660). MyGeneLog™. https://www.mygenelog.com/variants/rs12150660

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