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28 matches for
Gharahkhani P,
showing the first 20.
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics
Springelkamp H,
Iglesias AI,
Mishra A,
Höhn R,
Wojciechowski R,
Khawaja AP,
Nag A,
Wang YX,
Wang JJ,
Cuellar-Partida G,
Gibson J,
Bailey JN
and 71 more — show all
Vithana EN,
Gharahkhani P,
Boutin T,
Ramdas WD,
Zeller T,
Luben RN,
Yonova-Doing E,
Viswanathan AC,
Yazar S,
Cree AJ,
Haines JL,
Koh JY,
Souzeau E,
Wilson JF,
Amin N,
Müller C,
Venturini C,
Kearns LS,
Kang JH,
Tham YC,
Zhou T,
van Leeuwen EM,
Nickels S,
Sanfilippo P,
Liao J,
van der Linde H,
Zhao W,
van Koolwijk LM,
Zheng L,
Rivadeneira F,
Baskaran M,
van der Lee SJ,
Perera S,
de Jong PT,
Oostra BA,
Uitterlinden AG,
Fan Q,
Hofman A,
Tai ES,
Vingerling JR,
Sim X,
Wolfs RC,
Teo YY,
Lemij HG,
Khor CC,
Willemsen R,
Lackner KJ,
Aung T,
Jansonius NM,
Montgomery G,
Wild PS,
Young TL,
Burdon KP,
Hysi PG,
Pasquale LR,
Wong TY,
Klaver CC,
Hewitt AW,
Jonas JB,
Mitchell P,
Lotery AJ,
Foster PJ,
Vitart V,
Pfeiffer N,
Craig JE,
Mackey DA,
Hammond CJ,
Wiggs JL,
Cheng CY,
van Duijn CM,
MacGregor S
NEIGHBORHOOD Consortium
Human molecular genetics · 2017 · PMID 28073927
12 pages+
Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
Iglesias AI,
Mishra A,
Vitart V,
Bykhovskaya Y,
Höhn R,
Springelkamp H,
Cuellar-Partida G,
Gharahkhani P,
Bailey JNC,
Willoughby CE,
Li X,
Yazar S
and 47 more — show all
Nag A,
Khawaja AP,
Polašek O,
Siscovick D,
Mitchell P,
Tham YC,
Haines JL,
Kearns LS,
Hayward C,
Shi Y,
van Leeuwen EM,
Taylor KD,
Bonnemaijer P,
Rotter JI,
Martin NG,
Zeller T,
Mills RA,
Souzeau E,
Staffieri SE,
Jonas JB,
Schmidtmann I,
Boutin T,
Kang JH,
Lucas SEM,
Wong TY,
Beutel ME,
Wilson JF,
Uitterlinden AG,
Vithana EN,
Foster PJ,
Hysi PG,
Hewitt AW,
Khor CC,
Pasquale LR,
Montgomery GW,
Klaver CCW,
Aung T,
Pfeiffer N,
Mackey DA,
Hammond CJ,
Cheng CY,
Craig JE,
Rabinowitz YS,
Wiggs JL,
Burdon KP,
van Duijn CM,
MacGregor S
Blue Mountains Eye Study—GWAS group · NEIGHBORHOOD Consortium and 1 more consortia
Nature communications · 2018 · PMID 29760442 · open access
12 pages+
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error
Tedja MS,
Wojciechowski R,
Hysi PG,
Eriksson N,
Furlotte NA,
Verhoeven VJM,
Iglesias AI,
Meester-Smoor MA,
Tompson SW,
Fan Q,
Khawaja AP,
Cheng CY
and 86 more — show all
Höhn R,
Yamashiro K,
Wenocur A,
Grazal C,
Haller T,
Metspalu A,
Wedenoja J,
Jonas JB,
Wang YX,
Xie J,
Mitchell P,
Foster PJ,
Klein BEK,
Klein R,
Paterson AD,
Hosseini SM,
Shah RL,
Williams C,
Teo YY,
Tham YC,
Gupta P,
Zhao W,
Shi Y,
Saw WY,
Tai ES,
Sim XL,
Huffman JE,
Polašek O,
Hayward C,
Bencic G,
Rudan I,
Wilson JF,
Joshi PK,
Tsujikawa A,
Matsuda F,
Whisenhunt KN,
Zeller T,
van der Spek PJ,
Haak R,
Meijers-Heijboer H,
van Leeuwen EM,
Iyengar SK,
Lass JH,
Hofman A,
Rivadeneira F,
Uitterlinden AG,
Vingerling JR,
Lehtimäki T,
Raitakari OT,
Biino G,
Concas MP,
Schwantes-An TH,
Igo RP Jr,
Cuellar-Partida G,
Martin NG,
Craig JE,
Gharahkhani P,
Williams KM,
Nag A,
Rahi JS,
Cumberland PM,
Delcourt C,
Bellenguez C,
Ried JS,
Bergen AA,
Meitinger T,
Gieger C,
Wong TY,
Hewitt AW,
Mackey DA,
Simpson CL,
Pfeiffer N,
Pärssinen O,
Baird PN,
Vitart V,
Amin N,
van Duijn CM,
Bailey-Wilson JE,
Young TL,
Saw SM,
Stambolian D,
MacGregor S,
Guggenheim JA,
Tung JY,
Hammond CJ,
Klaver CCW
CREAM Consortium · 23andMe Research Team and 1 more consortia
Nature genetics · 2018 · PMID 29808027 · open access
12 pages+
Combined analysis of keratinocyte cancers identifies novel genome-wide loci
Liyanage UE,
Law MH,
Han X,
An J,
Ong JS,
Gharahkhani P,
Gordon S,
Neale RE,
Olsen CM,
MacGregor S,
Whiteman DC
23andMe Research Team
Human molecular genetics · 2019 · PMID 31174203 · open access
12 pages+
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
Bonnemaijer PWM,
Leeuwen EMV,
Iglesias AI,
Gharahkhani P,
Vitart V,
Khawaja AP,
Simcoe M,
Höhn R,
Cree AJ,
Igo RP,
Gerhold-Ay A,
Nickels S
and 16 more — show all
Wilson JF,
Hayward C,
Boutin TS,
Polašek O,
Aung T,
Khor CC,
Amin N,
Lotery AJ,
Wiggs JL,
Cheng CY,
Hysi PG,
Hammond CJ,
Thiadens AAHJ,
MacGregor S,
Klaver CCW,
Duijn CMV
International Glaucoma Genetics Consortium · NEIGHBORHOOD consortium and 1 more consortia
Communications biology · 2019 · PMID 31798171 · open access
12 pages+
Genome-wide association analysis of 95 549 individuals identifies novel loci and genes influencing optic disc morphology
Han X,
Qassim A,
An J,
Marshall H,
Zhou T,
Ong JS,
Hassall MM,
Hysi PG,
Foster PJ,
Khaw PT,
Mackey DA,
Gharahkhani P
and 4 more — show all
Human molecular genetics · 2019 · PMID 31809533
12 pages+
Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression
Craig JE,
Han X,
Qassim A,
Hassall M,
Cooke Bailey JN,
Kinzy TG,
Khawaja AP,
An J,
Marshall H,
Gharahkhani P,
Igo RP Jr,
Graham SL
and 47 more — show all
Healey PR,
Ong JS,
Zhou T,
Siggs O,
Law MH,
Souzeau E,
Ridge B,
Hysi PG,
Burdon KP,
Mills RA,
Landers J,
Ruddle JB,
Agar A,
Galanopoulos A,
White AJR,
Willoughby CE,
Andrew NH,
Best S,
Vincent AL,
Goldberg I,
Radford-Smith G,
Martin NG,
Montgomery GW,
Vitart V,
Hoehn R,
Wojciechowski R,
Jonas JB,
Aung T,
Pasquale LR,
Cree AJ,
Sivaprasad S,
Vallabh NA,
Viswanathan AC,
Pasutto F,
Haines JL,
Klaver CCW,
van Duijn CM,
Casson RJ,
Foster PJ,
Khaw PT,
Hammond CJ,
Mackey DA,
Mitchell P,
Lotery AJ,
Wiggs JL,
Hewitt AW,
MacGregor S
NEIGHBORHOOD consortium · UK Biobank Eye and Vision Consortium
Nature genetics · 2020 · PMID 31959993
12 pages+
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries
Gharahkhani P,
Jorgenson E,
Hysi P,
Khawaja AP,
Pendergrass S,
Han X,
Ong JS,
Hewitt AW,
Segrè AV,
Rouhana JM,
Hamel AR,
Igo RP Jr
and 67 more — show all
Choquet H,
Qassim A,
Josyula NS,
Cooke Bailey JN,
Bonnemaijer PWM,
Iglesias A,
Siggs OM,
Young TL,
Vitart V,
Thiadens AAHJ,
Karjalainen J,
Uebe S,
Melles RB,
Nair KS,
Luben R,
Simcoe M,
Amersinghe N,
Cree AJ,
Hohn R,
Poplawski A,
Chen LJ,
Rong SS,
Aung T,
Vithana EN,
Tamiya G,
Shiga Y,
Yamamoto M,
Nakazawa T,
Currant H,
Birney E,
Wang X,
Auton A,
Lupton MK,
Martin NG,
Ashaye A,
Olawoye O,
Williams SE,
Akafo S,
Ramsay M,
Hashimoto K,
Kamatani Y,
Akiyama M,
Momozawa Y,
Foster PJ,
Khaw PT,
Morgan JE,
Strouthidis NG,
Kraft P,
Kang JH,
Pang CP,
Pasutto F,
Mitchell P,
Lotery AJ,
Palotie A,
van Duijn C,
Haines JL,
Hammond C,
Pasquale LR,
Klaver CCW,
Hauser M,
Khor CC,
Mackey DA,
Kubo M,
Cheng CY,
Craig JE,
MacGregor S,
Wiggs JL
NEIGHBORHOOD consortium · ANZRAG consortium and 5 more consortia
Nature communications · 2021 · PMID 33627673 · open access
12 pages+
Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images
Currant H,
Hysi P,
Fitzgerald TW,
Gharahkhani P,
Bonnemaijer PWM,
Senabouth A,
Hewitt AW,
Atan D,
Aung T,
Charng J,
Choquet H,
Craig J
and 22 more — show all
Khaw PT,
Klaver CCW,
Kubo M,
Ong JS,
Pasquale LR,
Reisman CA,
Daniszewski M,
Powell JE,
Pébay A,
Simcoe MJ,
Thiadens AAHJ,
van Duijn CM,
Yazar S,
Jorgenson E,
MacGregor S,
Hammond CJ,
Mackey DA,
Wiggs JL,
Foster PJ,
Patel PJ,
Birney E,
Khawaja AP
UK Biobank Eye and Vision Consortium · International Glaucoma Genetics Consortium
PLoS genetics · 2021 · PMID 33979322 · open access
12 pages+
Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci
Han X,
Gharahkhani P,
Hamel AR,
Ong JS,
Rentería ME,
Mehta P,
Dong X,
Pasutto F,
Hammond C,
Young TL,
Hysi P,
Lotery AJ
and 18 more — show all
Jorgenson E,
Choquet H,
Hauser M,
Cooke Bailey JN,
Nakazawa T,
Akiyama M,
Shiga Y,
Fuller ZL,
Wang X,
Wang X,
Hewitt AW,
Craig JE,
Pasquale LR,
Mackey DA,
Wiggs JL,
Khawaja AP,
Segrè AV,
MacGregor S
23andMe Research Team · International Glaucoma Genetics Consortium
Nature genetics · 2023 · PMID 37386247 · open access
12 pages+
Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error
Fan Q,
Verhoeven VJ,
Wojciechowski R,
Barathi VA,
Hysi PG,
Guggenheim JA,
Höhn R,
Vitart V,
Khawaja AP,
Yamashiro K,
Hosseini SM,
Lehtimäki T
and 142 more — show all
Lu Y,
Haller T,
Xie J,
Delcourt C,
Pirastu M,
Wedenoja J,
Gharahkhani P,
Venturini C,
Miyake M,
Hewitt AW,
Guo X,
Mazur J,
Huffman JE,
Williams KM,
Polasek O,
Campbell H,
Rudan I,
Vatavuk Z,
Wilson JF,
Joshi PK,
McMahon G,
St Pourcain B,
Evans DM,
Simpson CL,
Schwantes-An TH,
Igo RP,
Mirshahi A,
Cougnard-Gregoire A,
Bellenguez C,
Blettner M,
Raitakari O,
Kähönen M,
Seppala I,
Zeller T,
Meitinger T,
Ried JS,
Gieger C,
Portas L,
van Leeuwen EM,
Amin N,
Uitterlinden AG,
Rivadeneira F,
Hofman A,
Vingerling JR,
Wang YX,
Wang X,
Tai-Hui Boh E,
Ikram MK,
Sabanayagam C,
Gupta P,
Tan V,
Zhou L,
Ho CE,
Lim W,
Beuerman RW,
Siantar R,
Tai ES,
Vithana E,
Mihailov E,
Khor CC,
Hayward C,
Luben RN,
Foster PJ,
Klein BE,
Klein R,
Wong HS,
Mitchell P,
Metspalu A,
Aung T,
Young TL,
He M,
Pärssinen O,
van Duijn CM,
Jin Wang J,
Williams C,
Jonas JB,
Teo YY,
Mackey DA,
Oexle K,
Yoshimura N,
Paterson AD,
Pfeiffer N,
Wong TY,
Baird PN,
Stambolian D,
Wilson JE,
Cheng CY,
Hammond CJ,
Klaver CC,
Saw SM,
Rahi JS,
Korobelnik JF,
Kemp JP,
Timpson NJ,
Smith GD,
Craig JE,
Burdon KP,
Fogarty RD,
Iyengar SK,
Chew E,
Janmahasatian S,
Martin NG,
MacGregor S,
Xu L,
Schache M,
Nangia V,
Panda-Jonas S,
Wright AF,
Fondran JR,
Lass JH,
Feng S,
Zhao JH,
Khaw KT,
Wareham NJ,
Rantanen T,
Kaprio J,
Pang CP,
Chen LJ,
Tam PO,
Jhanji V,
Young AL,
Döring A,
Raffel LJ,
Cotch MF,
Li X,
Yip SP,
Yap MK,
Biino G,
Vaccargiu S,
Fossarello M,
Fleck B,
Yazar S,
Tideman JW,
Tedja M,
Deangelis MM,
Morrison M,
Farrer L,
Zhou X,
Chen W,
Mizuki N,
Meguro A,
Mäkelä KM
Consortium for Refractive Error and Myopia
Nature communications · 2016 · PMID 27020472 · open access
10 pages
Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
MacGregor S,
Ong JS,
An J,
Han X,
Zhou T,
Siggs OM,
Law MH,
Souzeau E,
Sharma S,
Lynn DJ,
Beesley J,
Sheldrick B
and 20 more — show all
Mills RA,
Landers J,
Ruddle JB,
Graham SL,
Healey PR,
White AJR,
Casson RJ,
Best S,
Grigg JR,
Goldberg I,
Powell JE,
Whiteman DC,
Radford-Smith GL,
Martin NG,
Montgomery GW,
Burdon KP,
Mackey DA,
Gharahkhani P,
Craig JE,
Hewitt AW
Nature genetics · 2018 · PMID 30054594
10 pages
Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis
Ong JS,
An J,
Han X,
Law MH,
Nandakumar P,
Schumacher J,
Gockel I,
Bohmer A,
Jankowski J,
Palles C,
Olsen CM,
Neale RE
and 8 more — show all
23andMe Research team · Esophageal cancer consortium
Gut · 2022 · PMID 34187846 · open access
8 pages
Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology
Springelkamp H,
Mishra A,
Hysi PG,
Gharahkhani P,
Höhn R,
Khor CC,
Cooke Bailey JN,
Luo X,
Ramdas WD,
Vithana E,
Koh V,
Yazar S
and 45 more — show all
Xu L,
Forward H,
Kearns LS,
Amin N,
Iglesias AI,
Sim KS,
van Leeuwen EM,
Demirkan A,
van der Lee S,
Loon SC,
Rivadeneira F,
Nag A,
Sanfilippo PG,
Schillert A,
de Jong PT,
Oostra BA,
Uitterlinden AG,
Hofman A,
Zhou T,
Burdon KP,
Spector TD,
Lackner KJ,
Saw SM,
Vingerling JR,
Teo YY,
Pasquale LR,
Wolfs RC,
Lemij HG,
Tai ES,
Jonas JB,
Cheng CY,
Aung T,
Jansonius NM,
Klaver CC,
Craig JE,
Young TL,
Haines JL,
MacGregor S,
Mackey DA,
Pfeiffer N,
Wong TY,
Wiggs JL,
Hewitt AW,
van Duijn CM,
Hammond CJ
NEIGHBORHOOD Consortium
Genetic epidemiology · 2015 · PMID 25631615
6 pages
Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis
Gharahkhani P,
Fitzgerald RC,
Vaughan TL,
Palles C,
Gockel I,
Tomlinson I,
Buas MF,
May A,
Gerges C,
Anders M,
Becker J,
Kreuser N
and 57 more — show all
Noder T,
Venerito M,
Veits L,
Schmidt T,
Manner H,
Schmidt C,
Hess T,
Böhmer AC,
Izbicki JR,
Hölscher AH,
Lang H,
Lorenz D,
Schumacher B,
Hackelsberger A,
Mayershofer R,
Pech O,
Vashist Y,
Ott K,
Vieth M,
Weismüller J,
Nöthen MM,
Attwood S,
Barr H,
Chegwidden L,
de Caestecker J,
Harrison R,
Love SB,
MacDonald D,
Moayyedi P,
Prenen H,
Watson RGP,
Iyer PG,
Anderson LA,
Bernstein L,
Chow WH,
Hardie LJ,
Lagergren J,
Liu G,
Risch HA,
Wu AH,
Ye W,
Bird NC,
Shaheen NJ,
Gammon MD,
Corley DA,
Caldas C,
Moebus S,
Knapp M,
Peters WHM,
Neuhaus H,
Rösch T,
Ell C,
MacGregor S,
Pharoah P,
Whiteman DC,
Jankowski J,
Schumacher J
Barrett's and Esophageal Adenocarcinoma Consortium (BEACON) · Esophageal Adenocarcinoma GenEtics Consortium (EAGLE) and 1 more consortia
The Lancet. Oncology · 2016 · PMID 27527254 · open access
6 pages
Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases
An J,
Gharahkhani P,
Law MH,
Ong JS,
Han X,
Olsen CM,
Neale RE,
Lai J,
Vaughan TL,
Gockel I,
Thieme R,
Böhmer AC
and 6 more — show all
BEACON · 23andMe Research Team
Nature communications · 2019 · PMID 31527586 · open access
4 pages
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