Standard

Glaucoma

LOC107986141 · rs11710139

Where this position leads

Condition: Glaucoma

rs11710139 Condition: Glaucoma Glaucoma Condition rs11710139 rs11710139 LOC107986141

What the study found

Who was studied 11,018 European ancestry cases, 126,068 European ancestry controls.

The effect Each copy of the A allele carried 1.11 times the odds of Glaucoma (95% confidence interval 1.06-1.15); p = 5 × 10−8.

Where it sits Chromosome 3, band 3q25.1 — in an intron of LINC01214.

What each result means

A/A Two copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
Source

Questions about rs11710139

What is rs11710139?

rs11710139 is a single position in the genome, in or near the LOC107986141 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11710139 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs11710139 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11710139 come from?

GWAS Catalog, Nat Genet 2018, PMID:30054594. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (rs11710139). MyGeneLog™. https://www.mygenelog.com/variants/rs11710139

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