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Glaucoma

MYOF · rs61861119

Where this position leads

Condition: Glaucoma

rs61861119 Condition: Glaucoma Glaucoma Condition rs61861119 rs61861119 MYOF

What the study found

Who was studied 11,018 European ancestry cases, 126,068 European ancestry controls.

The effect Each copy of the A allele carried 1.10 times the odds of Glaucoma (95% confidence interval 1.05-1.14); p = 3 × 10−9.

Where it sits Chromosome 10, band 10q23.33 — between genes, 24 kb from XRCC6P1.

What each result means

A/A Two copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
Source

Questions about rs61861119

What is rs61861119?

rs61861119 is a single position in the genome, in or near the MYOF gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs61861119 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs61861119 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs61861119 come from?

GWAS Catalog, Nat Genet 2018, PMID:30054594. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (rs61861119). MyGeneLog™. https://www.mygenelog.com/variants/rs61861119

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