0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 90,939 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.01 lower; p = 4 × 10−11.
How common The A allele had a frequency of about 94% in the people studied.
Where it sits Chromosome 9, band 9q34.2 — in an intron of ABO.
What each result means
A/ATwo copies of the version the research linked to Vertical cup-disc ratio (multi-trait analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Vertical cup-disc ratio (multi-trait analysis). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Vertical cup-disc ratio (multi-trait analysis). This is the starting point the study compared everyone against.
rs8176662 is a single position in the genome, in or near the ABO gene. Published research associates it with vertical cup-disc ratio (multi-trait analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs8176662 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs8176662 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8176662 come from?
GWAS Catalog, Nature genetics 2020, PMID:31959993. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Vertical cup-disc ratio (multi-trait analysis) (rs8176662). MyGeneLog™. https://www.mygenelog.com/variants/rs8176662