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Ganglion cell inner plexiform layer (GCIPL) thickness

SNAP91 · rs13215351

What the study found

Who was studied 31,434 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.33 lower (95% confidence interval 0.23-0.43); p = 1 × 10−9.

How common The T allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 6, band 6q14.2 — in an intron of SNAP91.

What each result means

A/A No copy of the version the research linked to Ganglion cell inner plexiform layer (GCIPL) thickness. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Ganglion cell inner plexiform layer (GCIPL) thickness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Ganglion cell inner plexiform layer (GCIPL) thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13215351

What is rs13215351?

rs13215351 is a single position in the genome, in or near the SNAP91 gene. Published research associates it with ganglion cell inner plexiform layer (gcipl) thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13215351 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13215351 come from?

GWAS Catalog, PLoS genetics 2021, PMID:33979322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ganglion cell inner plexiform layer (GCIPL) thickness (rs13215351). MyGeneLog™. https://www.mygenelog.com/variants/rs13215351

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