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Intraocular pressure

PARD3B · rs11899425

Where this position leads

Condition: Intraocular Pressure

rs11899425 Condition: Intraocular Pressure Intraocular Pressure Condition rs11899425 rs11899425 PARD3B

What the study found

Who was studied 101,939 European ancestry cases.

The effect Each copy of the A allele shifted the measure 0.12 higher (95% confidence interval 0.081-0.159); p = 7 × 10−11.

Where it sits Chromosome 2, band 2q33.3 — in an intron of PARD3B.

What each result means

A/A Two copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
Source

Questions about rs11899425

What is rs11899425?

rs11899425 is a single position in the genome, in or near the PARD3B gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11899425 linked to?

On MyGeneLog this position is linked to Intraocular Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs11899425 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11899425 come from?

GWAS Catalog, JAMA ophthalmology 2020, PMID:32352494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Intraocular pressure (rs11899425). MyGeneLog™. https://www.mygenelog.com/variants/rs11899425

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