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Who was studied 418,642 British ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0144 higher (95% confidence interval 0.01-0.019); p = 6 × 10−11.
How common The G allele had a frequency of about 74% in the people studied.
Where it sits Chromosome 22, band 22q11.21 — in an intron of MICAL3.
What each result means
A/ANo copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
European journal of epidemiology · 2020 · PMID 31900758
Questions about rs13058527
What is rs13058527?
rs13058527 is a single position in the genome, in or near the MICAL3 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13058527 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs13058527 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13058527 come from?
GWAS Catalog, European journal of epidemiology 2020, PMID:31900758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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C-reactive protein levels (rs13058527). MyGeneLog™. https://www.mygenelog.com/variants/rs13058527