Standard

Glaucoma (primary open-angle)

LINC01214 · rs11710845

Where this position leads

Condition: Glaucoma

rs11710845 Condition: Glaucoma Glaucoma Condition rs11710845 rs11710845 LINC01214

What the study found

Who was studied 23,963 European ancestry cases, 306,942 European ancestry controls, 6,935 East Asian ancestry cases, 39,588 East Asian ancestry controls, 3,281 Sub-Saharan African ancestry cases, 2,791 Sub-Saharan African ancestry controls; replicated in 43,254 European ancestry cases, 1,471,118 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0586 lower; p = 4 × 10−12.

Where it sits Chromosome 3, band 3q25.1 — in a non-coding transcript of LINC01214.

What each result means

C/C No copy of the version the research linked to Glaucoma (primary open-angle). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Glaucoma (primary open-angle). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Glaucoma (primary open-angle). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11710845

What is rs11710845?

rs11710845 is a single position in the genome, in or near the LINC01214 gene. Published research associates it with glaucoma (primary open-angle). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11710845 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs11710845 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11710845 come from?

GWAS Catalog, Nature communications 2021, PMID:33627673. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (primary open-angle) (rs11710845). MyGeneLog™. https://www.mygenelog.com/variants/rs11710845

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