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Spherical equivalent

LOXL1 · rs893819

What the study found

Who was studied 95,827 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.08 higher (95% confidence interval 0.06-0.1); p = 3 × 10−11.

Where it sits Chromosome 15, band 15q24.1 — in an intron of LOXL1.

What each result means

A/A Two copies of the version the research linked to Spherical equivalent. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Spherical equivalent. That is a smaller link than two copies.
G/G No copy of the version the research linked to Spherical equivalent. This is the starting point the study compared everyone against.
Source

Questions about rs893819

What is rs893819?

rs893819 is a single position in the genome, in or near the LOXL1 gene. Published research associates it with spherical equivalent. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs893819 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs893819 come from?

GWAS Catalog, JAMA ophthalmology 2020, PMID:32352494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Spherical equivalent (rs893819). MyGeneLog™. https://www.mygenelog.com/variants/rs893819

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