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Central corneal thickness

LPAR1 · rs72748148

Where this position leads

Condition: Central Corneal Thickness

rs72748148 Condition: Central Corneal Thickness Central Corneal Thickness Condition rs72748148 rs72748148 LPAR1

What the study found

Who was studied 16,204 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 3.1 μm higher (95% confidence interval 2.17-4.02); p = 6 × 10−11.

How common The A allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 9, band 9q31.3 — in an intron of LPAR1.

What each result means

A/A Two copies of the version the research linked to Central corneal thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Central corneal thickness. That is a smaller link than two copies.
G/G No copy of the version the research linked to Central corneal thickness. This is the starting point the study compared everyone against.
Source

Questions about rs72748148

What is rs72748148?

rs72748148 is a single position in the genome, in or near the LPAR1 gene. Published research associates it with central corneal thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72748148 linked to?

On MyGeneLog this position is linked to Central Corneal Thickness. The research behind each link, and its sources, are set out on that condition page.

Does having rs72748148 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72748148 come from?

GWAS Catalog, Communications biology 2019, PMID:31798171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Central corneal thickness (rs72748148). MyGeneLog™. https://www.mygenelog.com/variants/rs72748148

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