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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 31,434 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.44 lower (95% confidence interval 0.36-0.52); p = 6 × 10−26.
How common The T allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 8, band 8q23.1 — between genes, 18.4 kb from RSPO2.
What each result means
C/CNo copy of the version the research linked to Retinal nerve fibre layer (RNFL) thickness. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Retinal nerve fibre layer (RNFL) thickness. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Retinal nerve fibre layer (RNFL) thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2021 · PMID 33979322 · open access
Questions about rs13271359
What is rs13271359?
rs13271359 is a single position in the genome, in or near the near RSPO2 gene. Published research associates it with retinal nerve fibre layer (rnfl) thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs13271359 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13271359 come from?
GWAS Catalog, PLoS genetics 2021, PMID:33979322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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