Sensitive

Basal cell carcinoma (MTAG)

near NOX4 · rs10830255

Where this position leads

Condition: Basal Cell Carcinoma

rs10830255 Condition: Basal Cell Carcinoma Basal Cell Carcinoma Condition rs10830255 rs10830255 near NOX4

What the study found

Who was studied 20,791 European ancestry cases, 286,893 European ancestry controls; replicated in 251,963 European ancestry cases, 2,271,667 European ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 1 × 10−182.

Where it sits Chromosome 11, band 11q14.3 — between genes, 13 kb from NOX4.

What each result means

A/A No copy of the version the research linked to Basal cell carcinoma (MTAG). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Basal cell carcinoma (MTAG). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Basal cell carcinoma (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10830255

What is rs10830255?

rs10830255 is a single position in the genome, in or near the near NOX4 gene. Published research associates it with basal cell carcinoma (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10830255 linked to?

On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs10830255 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10830255 come from?

GWAS Catalog, Nature communications 2022, PMID:36496446. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Basal cell carcinoma (MTAG) (rs10830255). MyGeneLog™. https://www.mygenelog.com/variants/rs10830255

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