The supplement industry's favourite word, and what the data supports.
Why this topic 'Slow ageing' is a supplement aisle, a subculture and a search term.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
Counted in Europe PMC, where the title or abstract names both this topic and that rsID. The number is papers, not evidence of a cause.
APOE
Lewy body disease
14 papers →APOE
Alzheimer's disease (late onset)
6 papers →MTHFR
Folate metabolism (MTHFR C677T)
5 papers →MCM8
Menopause (age at onset)
4 papers →APOE
LDL cholesterol
4 papers →BDNF
Smoking behavior
4 papers →EBF1
Longevity (90 years and older)
3 papers →near MRPS30
Breast cancer
2 papers →RIMS1
Schizophrenia
2 papers →MTHFR
Folate metabolism (MTHFR A1298C)
2 papers →ACTN3
Muscle fiber type ("sprinter gene")
2 papers →GC
Vitamin D levels
2 papers →MYH6
Electrocardiographic traits
2 papers →G6PC2
Fasting plasma glucose
2 papers →ABO
ABO blood type
2 papers →FTO
Menarche (age at onset)
2 papers →G6PD
G6PD deficiency (G6PD A-)
1 paper →CHRNA3
Smoking behavior
1 paper →DENND1A
Polycystic ovary syndrome
1 paper →MTCH2
Body mass index
1 paper →CFTR
Cystic fibrosis (F508del)
1 paper →TOMM40
C-reactive protein
1 paper →BRSK1
Menarche and menopause (age at onset)
1 paper →CNNM2
Intracranial aneurysm
1 paper →ZFP36L2
Polycystic ovary syndrome
1 paper →ZFP36L2
Polycystic ovary syndrome
1 paper →CDKN2B-AS1
Parental lifespan (9p21, the coronary artery disease locus)
1 paper →HK1
Hemoglobin
1 paper →OPRM1
Opioid receptor sensitivity
1 paper →HFE
Iron overload risk (hereditary hemochromatosis)
1 paper →CETP
Age-related macular degeneration
1 paper →NPPB
B-type natriuretic peptide levels
1 paper →SYCP2L
Menopause (age at onset)
1 paper →ZDHHC11
Pancreatic cancer
1 paper →TERT
Serum prostate-specific antigen levels
1 paper →APOC2
Triglycerides
1 paper →LAMA5
Colorectal cancer
1 paper →ABO
Pancreatic cancer
1 paper →GHSR
Height
1 paper →FUT2
Secretor status
1 paper →FUT2
Pediatric autoimmune diseases
1 paper →ALDH2
Alcohol flush reaction
1 paper →APOB
Cholesterol, total
1 paper →BDNP
Menarche (age at onset)
1 paper →TAS2R38
Bitter taste perception (PTC/PROP tasting)
1 paper →ZNF259
Triglyceride levels
1 paper →Europe PMC, title and abstract only, searched for “human longevity”, “healthy ageing”, “healthy aging”, “lifespan” alongside each published rsID. Full text was not counted: it returns every paper with an rsID buried in a supplementary table. Recounted monthly.
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Longevity and ageing. MyGeneLog™. https://www.mygenelog.com/topics/longevity
Longevity and ageing is this site's topic page for lifespan genetics — the supplement industry's favourite word, matched here against what the data actually supports.
Only partly, and less than marketing suggests. A variant appearing here shares a paper with longevity research, a much weaker claim than the supplement industry's favourite word implies.
"Slow ageing" is now a supplement aisle, a subculture and a search term all at once, which is what makes checking the genetics behind it worth doing properly.
Europe PMC is searched for human longevity, healthy ageing or lifespan appearing in a paper's title or abstract alongside a published rsID, recounted every month.