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Vitamin D levels

GC · rs2282679

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Where this position leads

Condition: Vitamin D Deficiency and the GC Gene

rs2282679 Condition: Vitamin D Deficiency and the GC Gene Vitamin D Deficiency and the GC Gene Condition rs2282679 GC

What each result means

G/G Published research associates this genotype with lower average circulating vitamin D levels, independent of diet or sun exposure — one of the strongest and most replicated genetic associations with vitamin D status.
T/G One copy of the variant. Published research associates this genotype with somewhat lower average circulating vitamin D (25-hydroxyvitamin D) levels.
T/T Typical vitamin D binding protein levels in published research — no added association with lower circulating vitamin D from this variant.
A blood test (25-hydroxyvitamin D) is the reliable way to know your actual level — this genotype only describes a population-level tendency. Talk to a doctor before starting supplementation.

Source: Wang et al. 2010, The Lancet — common genetic determinants of vitamin D insufficiency: a genome-wide association study.

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