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Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 96,598 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 5.5 mg/dL lower (95% confidence interval 4.64-6.36); p = 1 × 10−30.
How common The T allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 19, band 19q13.32 — between genes, 1.8 kb from APOE.
What ClinVar records
Classificationdrug response for Warfarin response; no assertion criteria provided (0 of 4 stars, 1 submitter), last evaluated 2010-08-31.
ClinVar record 619953NC_000019.10:g.44911194T>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs439401
What is rs439401?
rs439401 is a single position in the genome, in or near the APOC2 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs439401 linked to?
On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs439401?
Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (3 papers), blood sugar and insulin (2 papers), learning and focus (1 papers), longevity and ageing (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs439401 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs439401 come from?
GWAS Catalog, Nature 2010, PMID:20686565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
5 532228222231Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others31Total53Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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