Sensitive

Pancreatic cancer

ABO · rs505922

Where this position leads

Condition: Pancreatic Cancer

rs505922 Condition: Pancreatic Cancer Pancreatic Cancer Condition rs505922 rs505922 ABO

What the study found

Who was studied 1,771 European ancestry cases, 1,805 European ancestry controls; replicated in 2,120 European ancestry cases, 2,127 European ancestry controls.

The effect Each copy of the C allele carried 1.20 times the odds of Pancreatic cancer (95% confidence interval 1.12-1.28); p = 5 × 10−8.

How common The C allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 9, band 9q34.2 — in an intron of ABO.

What each result means

C/C Two copies of the version the research linked to Pancreatic cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Pancreatic cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Pancreatic cancer. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs505922

What is rs505922?

rs505922 is a single position in the genome, in or near the ABO gene. Published research associates it with pancreatic cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs505922 linked to?

On MyGeneLog this position is linked to Pancreatic Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs505922?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), depression and stress (1 papers), longevity and ageing (1 papers), sleep and insomnia (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs505922 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs505922 come from?

GWAS Catalog, Nat Genet 2009, PMID:19648918. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pancreatic cancer (rs505922). MyGeneLog™. https://www.mygenelog.com/variants/rs505922

← See all variants