Standard
Longevity (90 years and older)
EBF1 · rs2149954
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Longevity (90 years and older) — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Longevity (90 years and older).
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Longevity (90 years and older) compared to the general population.
Source
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
Deelen J,
Beekman M,
Uh HW,
Broer L,
Ayers KL,
Tan Q,
Kamatani Y,
Bennet AM,
Tamm R,
Trompet S,
Guðbjartsson DF,
Flachsbart F
and 75 more — show all
Rose G,
Viktorin A,
Fischer K,
Nygaard M,
Cordell HJ,
Crocco P,
van den Akker EB,
Böhringer S,
Helmer Q,
Nelson CP,
Saunders GI,
Alver M,
Andersen-Ranberg K,
Breen ME,
van der Breggen R,
Caliebe A,
Capri M,
Cevenini E,
Collerton JC,
Dato S,
Davies K,
Ford I,
Gampe J,
Garagnani P,
de Geus EJ,
Harrow J,
van Heemst D,
Heijmans BT,
Heinsen FA,
Hottenga JJ,
Hofman A,
Jeune B,
Jonsson PV,
Lathrop M,
Lechner D,
Martin-Ruiz C,
Mcnerlan SE,
Mihailov E,
Montesanto A,
Mooijaart SP,
Murphy A,
Nohr EA,
Paternoster L,
Postmus I,
Rivadeneira F,
Ross OA,
Salvioli S,
Sattar N,
Schreiber S,
Stefánsson H,
Stott DJ,
Tiemeier H,
Uitterlinden AG,
Westendorp RG,
Willemsen G,
Samani NJ,
Galan P,
Sørensen TI,
Boomsma DI,
Jukema JW,
Rea IM,
Passarino G,
de Craen AJ,
Christensen K,
Nebel A,
Stefánsson K,
Metspalu A,
Magnusson P,
Blanché H,
Christiansen L,
Kirkwood TB,
van Duijn CM,
Franceschi C,
Houwing-Duistermaat JJ,
Slagboom PE
Human molecular genetics · 2014 · PMID 24688116 · open access
Questions about rs2149954
What is rs2149954?
rs2149954 is a single position in the genome, in or near the EBF1 gene. Published research associates it with longevity (90 years and older). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2149954 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2149954 come from?
GWAS Catalog, Hum Mol Genet 2014, PMID:24688116. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants