Standard

Serum prostate-specific antigen levels

TERT · rs401681

What the study found

Who was studied 7,538 European ancestry individuals; replicated in 2,373 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 7 % higher; p = 1 × 10−10.

How common The C allele had a frequency of about 55% in the people studied.

Where it sits Chromosome 5, band 5p15.33 — in an intron of CLPTM1L.

What each result means

C/C Two copies of the version the research linked to Serum prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Serum prostate-specific antigen levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum prostate-specific antigen levels. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs401681

What is rs401681?

rs401681 is a single position in the genome, in or near the TERT gene. Published research associates it with serum prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs401681?

Subjects that appear in the title or abstract of the same papers as this rsID include smoking and vaping (2 papers), alcohol and the flush (1 papers), exercise and muscle (1 papers), learning and focus (1 papers), longevity and ageing (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs401681 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs401681 come from?

GWAS Catalog, Sci Transl Med 2010, PMID:21160077. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum prostate-specific antigen levels (rs401681). MyGeneLog™. https://www.mygenelog.com/variants/rs401681

← See all variants