Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 385 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
19 results in Digestive
Acute Gastritis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 2,691 cases and 617,490 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → DigestiveDuodenitis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 2,938 cases and 619,683 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveGallstones are hardened deposits that form in the gallbladder. A genome-wide meta-analysis of 43,639 cases and 506,798 controls found 75 risk loci and implicated genes that control how the gut and gallbladder move.
Read more → DigestiveCorneal Ulcer, as genome-wide studies have reported it: 6 positions from 1 study, the largest recording 2,091 cases and 629,795 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveHemorrhage from Gastrointestinal Ulcer, as genome-wide studies have reported it: 11 positions from 1 study, the largest recording 3,012 cases and 625,782 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveSialoadenitis, as genome-wide studies have reported it: 8 positions from 1 study, the largest recording 2,458 cases and 626,856 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveUlcer of Esophagus, as genome-wide studies have reported it: 11 positions from 1 study, the largest recording 3,164 cases and 625,341 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveAngiodysplasia of Intestine (without mention of hemorrhage), as genome-wide studies have reported it: 8 positions from 1 study, the largest recording 911 cases and 569,805 controls (African American or Afro-Caribbean ancestry, European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveDuodenal Ulcer, as genome-wide studies have reported it: 6 positions from 2 studies, the largest recording 17,117 cases and 867,208 controls (Japanese ancestry, European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → DigestiveNon-alcoholic Chronic Pancreatitis, as genome-wide studies have reported it: 3 positions from 1 study, the largest recording 584 cases and 6,040 controls (European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveAcute Pancreatitis, as genome-wide studies have reported it: 6 positions from 3 studies, the largest recording 10,630 cases and 844,679 controls (European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveInfantile Hypertrophic Pyloric Stenosis, as genome-wide studies have reported it: 2 positions from 1 study, the largest recording 1,395 cases and 4,438 controls. Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → DigestiveGastroesophageal Reflux Disease, as genome-wide studies have reported it: 12 positions from 2 studies, the largest recording 129,080 cases and 473,524 controls (European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → DigestiveGastric Ulcer, as genome-wide studies have reported it: 4 positions from 3 studies, the largest recording 28,682 cases and 867,208 controls (Japanese ancestry, European ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → DigestiveIrritable Bowel Syndrome, as genome-wide studies have reported it: 10 positions from 4 studies, the largest recording 68,267 cases and 860,556 controls (European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → DigestiveUmbilical Hernia, as genome-wide studies have reported it: 63 positions from 3 studies, the largest recording 20,188 cases and 602,677 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → DigestiveSix risk variants for colon polyps, surfaced from a 220-phenotype genetic atlas built across Japanese, European, and Finnish populations — one small slice of a much bigger study.
Read more → DigestiveA disease of the first weeks of life, in which the bile ducts outside the liver progressively scar shut. A genome-wide study of 200 Chinese infants with the condition found one locus near a gene involved in inflammation — evidence for a genetic contribution to a disease usually described only by what triggers it, which remains unknown.
Read more → DigestiveAn allergic disease of the esophagus whose top genetic locus, CAPN14, was shown in the lab to be switched on by the same allergic signal (IL-13) thought to drive the disease itself.
Read more →One diagnosed condition or measurable trait covered properly: what it actually is, what causes it, how common it is, how it is diagnosed, and the specific variants with a replicated link to it — every claim sourced from published research.
No. Every page here is informational, not a diagnosis. A result should be discussed with a doctor or a licensed genetic counselor, never acted on alone.
Because they are not disorders. Height, ABO blood group and a handful of others describe a measurable characteristic with nothing to diagnose — "Trait" says so plainly instead of implying a disease that is not one.
Only after a replicated association in published research, verified against the primary study rather than a gene name or a marketing claim — the same discipline the variant pages themselves follow.