Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 385 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
25 results in Condition
Dyshidrosis, as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 2,455 cases and 626,220 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionChondrocalcinosis, as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 3,282 cases and 625,577 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionComplex Regional/central Pain Syndrome, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 3,122 cases and 625,178 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → ConditionCostochondritis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 902 cases and 567,630 controls (African American or Afro-Caribbean ancestry, European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → ConditionSuperficial Keratitis, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 2,528 cases and 623,139 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionPyogenic Granuloma, as genome-wide studies have reported it: 5 positions from 1 study, the largest recording 1,065 cases and 569,509 controls (African American or Afro-Caribbean ancestry, European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionRespiratory Insufficiency, as genome-wide studies have reported it: 6 positions from 1 study, the largest recording 2,918 cases and 624,478 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → ConditionCholelithiasis with Acute Cholecystitis, as genome-wide studies have reported it: 7 positions from 1 study, the largest recording 2,327 cases and 627,131 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → ConditionPsoriatic Arthropathy, as genome-wide studies have reported it: 7 positions from 1 study, the largest recording 3,723 cases and 628,576 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → ConditionHypocalcemia, as genome-wide studies have reported it: 8 positions from 1 study, the largest recording 3,109 cases and 624,208 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → ConditionMeningitis, as genome-wide studies have reported it: 10 positions from 2 studies, the largest recording 1,180 cases and 570,786 controls (African American or Afro-Caribbean ancestry, European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → ConditionA 2019 UK Biobank study used prescription records themselves, not diagnosis codes, as the trait to study -- and found that genetics behind who takes diabetes or peptic-ulcer drugs mostly recovers the genes already known to cause the underlying diseases.
Read more → ConditionA reproductive condition and a mood disorder that look unrelated, but a 2020 study built specifically to test the overlap found a real, significant shared genetic architecture between them -- plus an unexpected link to stomach lining abnormality.
Read more → ConditionSmall pockets that form in the colon wall, common with age — a 2018 UK Biobank study of over 409,000 people found 39 new risk loci in total, 17 of them in this site's own catalogue, several pointing toward connective-tissue genes.
Read more → ConditionSwollen, inflamed veins in the lowest part of the rectum or anus, common enough that a 2021 study analyzed 944,133 people at once — finding a genome-wide significant, if individually small, risk variant near BMP8B.
Read more → ConditionA brain tumor arising from glial cells, about 50% more common in men than women — three studies from 2009 to 2018 found 6 contributing variants, on this page, including one whose effect differs by sex.
Read more → ConditionA balloon-like weak spot in a brain artery wall, affecting about 2% of people — three studies from 2008 to 2012 found 6 contributing variants, on this page, including one confirmed twice independently.
Read more → ConditionA 199,000-person Japanese GWAS more than doubled the number of known genetic risk loci for kidney and urinary stones — 6 of the 14 it found are on this page.
Read more → ConditionA chronic inflammatory arthritis of the spine and pelvis, driven mainly by HLA-B27 — three separate studies have also found 6 other variants, on this page, each independently.
Read more → ConditionThe largest GWAS of primary sclerosing cholangitis to date found 4 new risk loci and showed the disease is genetically distinct from the inflammatory bowel disease it so often accompanies.
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One diagnosed condition or measurable trait covered properly: what it actually is, what causes it, how common it is, how it is diagnosed, and the specific variants with a replicated link to it — every claim sourced from published research.
No. Every page here is informational, not a diagnosis. A result should be discussed with a doctor or a licensed genetic counselor, never acted on alone.
Because they are not disorders. Height, ABO blood group and a handful of others describe a measurable characteristic with nothing to diagnose — "Trait" says so plainly instead of implying a disease that is not one.
Only after a replicated association in published research, verified against the primary study rather than a gene name or a marketing claim — the same discipline the variant pages themselves follow.