Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 385 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
10 results in Respiratory
Acute Tonsillitis, as genome-wide studies have reported it: 8 positions from 1 study, the largest recording 1,539 cases and 626,131 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → RespiratoryAcute Laryngitis and Tracheitis, as genome-wide studies have reported it: 7 positions from 1 study, the largest recording 885 cases and 567,247 controls (African American or Afro-Caribbean ancestry, European ancestry). Built from the GWAS Catalog's records and rebuilt when a new position is reported; the figures are the studies'.
Read more → RespiratoryChronic Inflammatory Sinonasal Disease, as genome-wide studies have reported it: 2 positions from 1 study, the largest recording 19,901 cases and 199,208 controls. Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Read more → RespiratoryPharyngeal Disease, as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 33,157 cases and 199,208 controls. Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
Read more → RespiratoryNasal polyps and asthma often arrive together, and the pair is harder to treat than either alone. A 2025 study found 131 associations across the two and showed that 71 loci act on both. 15 of its positions for the polyp disease are in this catalogue.
Read more → RespiratoryA progressive scarring disease of the lungs with a strong genetic component: two genome-wide studies found risk variants in TOLLIP, SPPL2C and AKAP13 beside the well-known MUC5B signal — and one TOLLIP variant that protects against getting the disease but predicts worse survival in those who get it anyway.
Read more → RespiratoryThe first genome-wide study of childhood sleep apnea, run separately by ancestry and by sex in nearly 1,500 children — with one risk locus that held up in both African American and European American children alike.
Read more → RespiratoryScarring and stiffening of the tissue between the lungs' air sacs. The genetics of the largest subtype, idiopathic pulmonary fibrosis, keeps returning to a mucus gene and a telomere gene, and this page's four variants are newer loci from the same large study, in different biology again.
Read more → RespiratoryThe largest study of its kind found that childhood asthma and adult asthma do not have the same genetics — and that the allergy marker doctors have measured for decades is largely beside the point.
Read more → RespiratoryHow well a pair of lungs works is heritable and measurable, and it is also mostly the result of what has been breathed. Both halves are true, and the second one is larger.
Read more →One diagnosed condition or measurable trait covered properly: what it actually is, what causes it, how common it is, how it is diagnosed, and the specific variants with a replicated link to it — every claim sourced from published research.
No. Every page here is informational, not a diagnosis. A result should be discussed with a doctor or a licensed genetic counselor, never acted on alone.
Because they are not disorders. Height, ABO blood group and a handful of others describe a measurable characteristic with nothing to diagnose — "Trait" says so plainly instead of implying a disease that is not one.
Only after a replicated association in published research, verified against the primary study rather than a gene name or a marketing claim — the same discipline the variant pages themselves follow.