Continuously updated · last reviewed Sep 5, 2026
Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 27 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
3 results in Immunologic
A 32-base-pair deletion in the CCR5 gene that removes a key HIV-1 entry receptor from immune cells; two copies confer strong resistance to CCR5-tropic HIV-1, while one copy slows disease progression without preventing infection.
Read more → ImmunologicA lifelong inflammatory bowel disease that can affect any part of the digestive tract. Its genetics are unusually well mapped — NOD2 was the first susceptibility gene ever found for a common complex disease, and IL23R showed a drug class where to aim.
Read more → ImmunologicA common FUT2 variant determines whether ABO blood-group antigens appear in saliva, gut mucus and other secretions; the roughly one in five people who are "non-secretors" are strongly resistant to the dominant norovirus strains.
Read more →