Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 385 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
3 results in Dental
One of the most common inflammatory diseases in the world, with an estimated heritability around 50%. Two studies behind this page found different genetic signals -- one from a large European meta-analysis, one specific to a localized form of the disease in an isolated Italian population.
Read more → DentalTeeth that never form, not teeth that come in late — a different question from this site's tooth-eruption-timing page. A study of nearly 2,000 people with congenitally missing teeth found nine risk variants, several of them specific to which particular teeth go missing.
Read more → DentalThe most common chronic disease in children. One genome-wide-significant susceptibility gene has been found; the two things people actually reach for — fluoride toothpaste and xylitol gum — have a real evidence base of their own, and it is not the same size for each.
Read more →One diagnosed condition or measurable trait covered properly: what it actually is, what causes it, how common it is, how it is diagnosed, and the specific variants with a replicated link to it — every claim sourced from published research.
No. Every page here is informational, not a diagnosis. A result should be discussed with a doctor or a licensed genetic counselor, never acted on alone.
Because they are not disorders. Height, ABO blood group and a handful of others describe a measurable characteristic with nothing to diagnose — "Trait" says so plainly instead of implying a disease that is not one.
Only after a replicated association in published research, verified against the primary study rather than a gene name or a marketing claim — the same discipline the variant pages themselves follow.