Each page covers one condition properly: what it actually is and what it feels like, what causes it, how common it really is and in whom, and how it's diagnosed — followed by the specific variants with a replicated link to it, and, where the research supports it, how genetics can change the way a medicine behaves.
Written in two registers so one page serves both readers: plain language first, then a clinical detail section with the precise terminology, effect sizes and diagnostic thresholds. Every claim is sourced from freely-available published research and cited on the page, so you can check us — or hand the page to your doctor. 385 conditions so far, growing continuously, and free to reuse with attribution (CC BY 4.0).
5 results in Sensory
The largest genetic study of hearing loss, in 723,266 people, found 48 loci — and traced the common-variant signal to a specific structure in the inner ear, the stria vascularis. This page holds 15 of those positions.
Read more → SensoryThe leading cause of blindness worldwide, though surgery reliably fixes it where it is available. A locus near CRYAA — a gene the eye's lens is physically built from — showed its activity actually falling in human lens tissue as cataract severity rises.
Read more → SensoryThe bitter taste receptor T2R38 is not only on the tongue. It also lines the sinuses, where it detects bacterial signalling molecules and answers with nitric oxide — and the genotype that tastes nothing defends the sinuses less well.
Read more → SensoryOdorant receptors are the largest gene family in the human genome, and they differ enormously between people. The result is that two people can meet the same molecule and only one of them smells anything at all.
Read more → SensoryThree coding changes in one bitter receptor gene decide whether compounds like PTC and PROP taste intensely bitter or of almost nothing. It is the strongest genetic association on this site, and one of the oldest known human polymorphisms.
Read more →One diagnosed condition or measurable trait covered properly: what it actually is, what causes it, how common it is, how it is diagnosed, and the specific variants with a replicated link to it — every claim sourced from published research.
No. Every page here is informational, not a diagnosis. A result should be discussed with a doctor or a licensed genetic counselor, never acted on alone.
Because they are not disorders. Height, ABO blood group and a handful of others describe a measurable characteristic with nothing to diagnose — "Trait" says so plainly instead of implying a disease that is not one.
Only after a replicated association in published research, verified against the primary study rather than a gene name or a marketing claim — the same discipline the variant pages themselves follow.