Angiodysplasia of Intestine (without mention of hemorrhage), as genome-wide studies have reported it: 8 positions from 1 study, the largest recording 911 cases and 569,805 controls (African American or Afro-Caribbean ancestry, European ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Angiodysplasia of Intestine (without mention of hemorrhage) — filed in the GWAS Catalog as "Angiodysplasia of intestine (without mention of hemorrhage) (PheCode 556.11)" — is a condition this catalogue follows as its positions arrive. This page is assembled by MyGeneLog's own code from the catalogue's records and the studies' own listings: 8 positions from 1 study, and no sentence written by hand. It is rebuilt as new positions are reported, so what it says is what the records say today.
Verma A et al. 2024, in Science — Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Studied in 911 cases and 569,805 controls (African American or Afro-Caribbean ancestry, European ancestry). From it, 8 positions on this page: rs186886479 (UGGT2), rs200401136 (OARD1), rs529485874 (near MIR4455), rs554840714 (near GUCY1A2), rs537826069 (near LINC02113), rs186687949 (LOHAN2), rs540246290 (near CYCSP42), rs576948131 (DOK5). PMID:39024449.
The catalogue maps the 8 positions to 8 genes: UGGT2, OARD1, MIR4455, GUCY1A2, LINC02113, LOHAN2, CYCSP42, DOK5. That mapping says where a position sits, in a gene or beside one — not what it does. For what each study measured, follow its citation above.
The strongest association in the records is rs186886479 in UGGT2, reported by Verma A et al. 2024 at P = 3 × 10-14.
Association records say which positions differ, on average, between people with Angiodysplasia of Intestine (without mention of hemorrhage) and people without. They do not describe the condition, say how common it is, or tell anyone what to do, so this page does not either. For a single position, open its variant page: it gives that study's record in fixed sentences, with ClinVar's where there is one.
A genotype does not diagnose Angiodysplasia of Intestine (without mention of hemorrhage); a clinician does. No guideline uses the 8 variants on this page to predict it, screen for it or confirm it.
This page was assembled by code from association records. It holds no clinical guidance, because its sources hold none: a genome-wide study reports which positions differ between people with a condition and people without, at the population level, and that is all this page repeats. A question about a symptom, a test or a treatment belongs with a clinician.
What a 23andMe/AncestryDNA export or raw VCF can and can't tell you about Angiodysplasia of Intestine (without mention of hemorrhage) comes down to these specific, well-studied positions — not a diagnosis.
UGGT2 · rs186886479
See detailed info →OARD1 · rs200401136
See detailed info →near MIR4455 · rs529485874
See detailed info →near GUCY1A2 · rs554840714
See detailed info →near LINC02113 · rs537826069
See detailed info →LOHAN2 · rs186687949
See detailed info →near CYCSP42 · rs540246290
See detailed info →DOK5 · rs576948131
See detailed info →Databases, guidelines and references
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Angiodysplasia of Intestine (without mention of hemorrhage). MyGeneLog™. https://www.mygenelog.com/conditions/angiodysplasia-of-intestine-without-mention-of-hemorrhage
Angiodysplasia of Intestine (without mention of hemorrhage) is the condition the GWAS Catalog files under "Angiodysplasia of intestine (without mention of hemorrhage) (PheCode 556.11)". This page does not define it in its own words; it lists what genome-wide studies have reported: 8 positions from 1 study, with each study's sample and citation.
Genome-wide studies have reported 8 associated positions; the largest study behind this page recorded 911 cases and 569,805 controls (African American or Afro-Caribbean ancestry, European ancestry). Each common variant has a small effect, and an association in a population is not a cause in any one person.
The catalogue maps the positions to 8 genes: UGGT2, OARD1, MIR4455, GUCY1A2, LINC02113, LOHAN2, CYCSP42, DOK5. These are where the positions sit, not proof of how they act.
No. Each variant shifts the odds only slightly, and only on average across many people. No guideline predicts Angiodysplasia of Intestine (without mention of hemorrhage) from a genotype; a clinician diagnoses it.
Free to reuse. This page's text is original writing from freely-available research, licensed CC BY 4.0 — reuse it, including commercially, with attribution to MyGeneLog™. It's general research-derived information, not medical advice or a diagnosis — see Terms of Use.