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23 matches for
Silverman EK,
showing the first 20.
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry
Lutz SM,
Cho MH,
Young K,
Hersh CP,
Castaldi PJ,
McDonald ML,
Regan E,
Mattheisen M,
DeMeo DL,
Parker M,
Foreman M,
Make BJ
and 12 more — show all
Jensen RL,
Casaburi R,
Lomas DA,
Bhatt SP,
Bakke P,
Gulsvik A,
Crapo JD,
Beaty TH,
Laird NM,
Lange C,
Hokanson JE,
Silverman EK
ECLIPSE Investigators · COPDGene Investigators
BMC genetics · 2015 · PMID 26634245 · open access
12 pages+
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
Wain LV,
Shrine N,
Artigas MS,
Erzurumluoglu AM,
Noyvert B,
Bossini-Castillo L,
Obeidat M,
Henry AP,
Portelli MA,
Hall RJ,
Billington CK,
Rimington TL
and 94 more — show all
Fenech AG,
John C,
Blake T,
Jackson VE,
Allen RJ,
Prins BP,
Campbell A,
Porteous DJ,
Jarvelin MR,
Wielscher M,
James AL,
Hui J,
Wareham NJ,
Zhao JH,
Wilson JF,
Joshi PK,
Stubbe B,
Rawal R,
Schulz H,
Imboden M,
Probst-Hensch NM,
Karrasch S,
Gieger C,
Deary IJ,
Harris SE,
Marten J,
Rudan I,
Enroth S,
Gyllensten U,
Kerr SM,
Polasek O,
Kähönen M,
Surakka I,
Vitart V,
Hayward C,
Lehtimäki T,
Raitakari OT,
Evans DM,
Henderson AJ,
Pennell CE,
Wang CA,
Sly PD,
Wan ES,
Busch R,
Hobbs BD,
Litonjua AA,
Sparrow DW,
Gulsvik A,
Bakke PS,
Crapo JD,
Beaty TH,
Hansel NN,
Mathias RA,
Ruczinski I,
Barnes KC,
Bossé Y,
Joubert P,
van den Berge M,
Brandsma CA,
Paré PD,
Sin DD,
Nickle DC,
Hao K,
Gottesman O,
Dewey FE,
Bruse SE,
Carey DJ,
Kirchner HL,
Jonsson S,
Thorleifsson G,
Jonsdottir I,
Gislason T,
Stefansson K,
Schurmann C,
Nadkarni G,
Bottinger EP,
Loos RJ,
Walters RG,
Chen Z,
Millwood IY,
Vaucher J,
Kurmi OP,
Li L,
Hansell AL,
Brightling C,
Zeggini E,
Cho MH,
Silverman EK,
Sayers I,
Trynka G,
Morris AP,
Strachan DP,
Hall IP,
Tobin MD
Understanding Society Scientific Group · Geisinger-Regeneron DiscovEHR Collaboration
Nature genetics · 2017 · PMID 28166213 · open access
12 pages+
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
Shrine N,
Guyatt AL,
Erzurumluoglu AM,
Jackson VE,
Hobbs BD,
Melbourne CA,
Batini C,
Fawcett KA,
Song K,
Sakornsakolpat P,
Li X,
Boxall R
and 99 more — show all
Reeve NF,
Obeidat M,
Zhao JH,
Wielscher M,
Weiss S,
Kentistou KA,
Kentistou KA,
Cook JP,
Sun BB,
Zhou J,
Hui J,
Karrasch S,
Imboden M,
Harris SE,
Marten J,
Enroth S,
Kerr SM,
Surakka I,
Vitart V,
Lehtimäki T,
Allen RJ,
Bakke PS,
Beaty TH,
Bleecker ER,
Bossé Y,
Brandsma CA,
Chen Z,
Crapo JD,
Danesh J,
DeMeo DL,
Dudbridge F,
Ewert R,
Gieger C,
Gulsvik A,
Hansell AL,
Hao K,
Hoffman JD,
Hokanson JE,
Homuth G,
Joshi PK,
Joubert P,
Langenberg C,
Li X,
Li L,
Lin K,
Lind L,
Locantore N,
Luan J,
Mahajan A,
Maranville JC,
Murray A,
Nickle DC,
Packer R,
Parker MM,
Paynton ML,
Porteous DJ,
Porteous DJ,
Prokopenko D,
Qiao D,
Rawal R,
Runz H,
Sayers I,
Sin DD,
Smith BH,
Soler Artigas M,
Sparrow D,
Tal-Singer R,
Timmers PRHJ,
Van den Berge M,
Whittaker JC,
Woodruff PG,
Yerges-Armstrong LM,
Troyanskaya OG,
Raitakari OT,
Kähönen M,
Polašek O,
Gyllensten U,
Rudan I,
Deary IJ,
Probst-Hensch NM,
Schulz H,
James AL,
Wilson JF,
Stubbe B,
Zeggini E,
Jarvelin MR,
Wareham N,
Silverman EK,
Hayward C,
Morris AP,
Butterworth AS,
Scott RA,
Walters RG,
Meyers DA,
Cho MH,
Strachan DP,
Hall IP,
Tobin MD,
Wain LV
Understanding Society Scientific Group
Nature genetics · 2019 · PMID 30804560 · open access
12 pages+
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
Sakornsakolpat P,
Prokopenko D,
Lamontagne M,
Reeve NF,
Guyatt AL,
Jackson VE,
Shrine N,
Qiao D,
Bartz TM,
Kim DK,
Lee MK,
Latourelle JC
and 42 more — show all
Li X,
Morrow JD,
Obeidat M,
Wyss AB,
Bakke P,
Barr RG,
Beaty TH,
Belinsky SA,
Brusselle GG,
Crapo JD,
de Jong K,
DeMeo DL,
Fingerlin TE,
Gharib SA,
Gulsvik A,
Hall IP,
Hokanson JE,
Kim WJ,
Lomas DA,
London SJ,
Meyers DA,
O'Connor GT,
Rennard SI,
Schwartz DA,
Sliwinski P,
Sparrow D,
Strachan DP,
Tal-Singer R,
Tesfaigzi Y,
Vestbo J,
Vonk JM,
Yim JJ,
Zhou X,
Bossé Y,
Manichaikul A,
Lahousse L,
Silverman EK,
Boezen HM,
Wain LV,
Tobin MD,
Hobbs BD,
Cho MH
SpiroMeta Consortium · International COPD Genetics Consortium
Nature genetics · 2019 · PMID 30804561 · open access
12 pages+
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
Shrine N,
Izquierdo AG,
Chen J,
Packer R,
Hall RJ,
Guyatt AL,
Batini C,
Thompson RJ,
Pavuluri C,
Malik V,
Hobbs BD,
Moll M
and 136 more — show all
Kim W,
Tal-Singer R,
Bakke P,
Fawcett KA,
John C,
Coley K,
Piga NN,
Pozarickij A,
Lin K,
Millwood IY,
Chen Z,
Li L,
Wijnant SRA,
Lahousse L,
Brusselle G,
Uitterlinden AG,
Manichaikul A,
Oelsner EC,
Rich SS,
Barr RG,
Kerr SM,
Vitart V,
Brown MR,
Wielscher M,
Imboden M,
Jeong A,
Bartz TM,
Gharib SA,
Flexeder C,
Karrasch S,
Gieger C,
Peters A,
Stubbe B,
Hu X,
Ortega VE,
Meyers DA,
Bleecker ER,
Gabriel SB,
Gupta N,
Smith AV,
Luan J,
Zhao JH,
Hansen AF,
Langhammer A,
Willer C,
Bhatta L,
Porteous D,
Smith BH,
Campbell A,
Sofer T,
Lee J,
Daviglus ML,
Yu B,
Lim E,
Xu H,
O'Connor GT,
Thareja G,
Albagha OME,
Suhre K,
Granell R,
Faquih TO,
Hiemstra PS,
Slats AM,
Mullin BH,
Hui J,
James A,
Beilby J,
Patasova K,
Hysi P,
Koskela JT,
Wyss AB,
Jin J,
Sikdar S,
Lee M,
May-Wilson S,
Pirastu N,
Kentistou KA,
Joshi PK,
Timmers PRHJ,
Williams AT,
Free RC,
Wang X,
Morrison JL,
Gilliland FD,
Chen Z,
Wang CA,
Foong RE,
Harris SE,
Taylor A,
Redmond P,
Cook JP,
Mahajan A,
Lind L,
Palviainen T,
Lehtimäki T,
Raitakari OT,
Kaprio J,
Rantanen T,
Pietiläinen KH,
Cox SR,
Pennell CE,
Hall GL,
Gauderman WJ,
Brightling C,
Wilson JF,
Vasankari T,
Laitinen T,
Salomaa V,
Mook-Kanamori DO,
Timpson NJ,
Zeggini E,
Dupuis J,
Hayward C,
Brumpton B,
Langenberg C,
Weiss S,
Homuth G,
Schmidt CO,
Probst-Hensch N,
Jarvelin MR,
Morrison AC,
Polasek O,
Rudan I,
Lee JH,
Sayers I,
Rawlins EL,
Dudbridge F,
Silverman EK,
Strachan DP,
Walters RG,
Morris AP,
London SJ,
Cho MH,
Wain LV,
Hall IP,
Tobin MD
China Kadoorie Biobank Collaborative Group · Qatar Genome Program Research (QGPR) Consortium
Nature genetics · 2023 · PMID 36914875 · open access
12 pages+
Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium
Jiang MZ,
Gaynor SM,
Li X,
Van Buren E,
Stilp A,
Stilp A,
Buth E,
Wang FF,
Manansala R,
Gogarten SM,
Li Z,
Polfus LM
and 35 more — show all
Salimi S,
Bis JC,
Pankratz N,
Yanek LR,
Durda P,
Tracy RP,
Rich SS,
Rotter JI,
Mitchell BD,
Lewis JP,
Psaty BM,
Pratte KA,
Silverman EK,
Kaplan RC,
Avery C,
North KE,
Mathias RA,
Faraday N,
Lin H,
Wang B,
Carson AP,
Norwood AF,
Gibbs RA,
Kooperberg C,
Lundin J,
Peters U,
Dupuis J,
Hou L,
Fornage M,
Benjamin EJ,
Reiner AP,
Bowler RP,
Lin X,
Auer PL,
Raffield LM
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Inflammation Working Group
Human molecular genetics · 2024 · PMID 38747556
11 pages
Genome-Wide Gene-by-Smoking Interaction Study of Chronic Obstructive Pulmonary Disease
Kim W,
Prokopenko D,
Sakornsakolpat P,
Hobbs BD,
Lutz SM,
Hokanson JE,
Wain LV,
Melbourne CA,
Shrine N,
Tobin MD,
Silverman EK,
Cho MH
and 1 more — show all
American journal of epidemiology · 2021 · PMID 33106845
6 pages
Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution
Boueiz A,
Lutz SM,
Cho MH,
Hersh CP,
Bowler RP,
Washko GR,
Halper-Stromberg E,
Bakke P,
Gulsvik A,
Laird NM,
Beaty TH,
Coxson HO
and 4 more — show all
COPDGene and ECLIPSE Investigators
American journal of respiratory and critical care medicine · 2017 · PMID 27669027
4 pages
A systematic analysis of protein-altering exonic variants in chronic obstructive pulmonary disease
Moll M,
Jackson VE,
Yu B,
Grove ML,
London SJ,
Gharib SA,
Bartz TM,
Sitlani CM,
Dupuis J,
O'Connor GT,
Xu H,
Cassano PA
and 21 more — show all
Patchen BK,
Kim WJ,
Park J,
Kim KH,
Han B,
Barr RG,
Manichaikul A,
Nguyen JN,
Rich SS,
Lahousse L,
Terzikhan N,
Brusselle G,
Sakornsakolpat P,
Liu J,
Benway CJ,
Hall IP,
Tobin MD,
Wain LV,
Silverman EK,
Cho MH,
Hobbs BD
American journal of physiology. Lung cellular and molecular physiology · 2021 · PMID 33909500
4 pages
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis
Cho MH,
McDonald ML,
Zhou X,
Mattheisen M,
Castaldi PJ,
Hersh CP,
Demeo DL,
Sylvia JS,
Ziniti J,
Laird NM,
Lange C,
Litonjua AA
and 17 more — show all
Sparrow D,
Casaburi R,
Barr RG,
Regan EA,
Make BJ,
Hokanson JE,
Lutz S,
Dudenkov TM,
Farzadegan H,
Hetmanski JB,
Tal-Singer R,
Lomas DA,
Bakke P,
Gulsvik A,
Crapo JD,
Silverman EK,
Beaty TH
NETT Genetics, ICGN, ECLIPSE and COPDGene Investigators
The Lancet. Respiratory medicine · 2014 · PMID 24621683
3 pages
A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes
Cho MH,
Castaldi PJ,
Hersh CP,
Hobbs BD,
Barr RG,
Tal-Singer R,
Bakke P,
Gulsvik A,
San José Estépar R,
Van Beek EJ,
Coxson HO,
Lynch DA
and 5 more — show all
NETT Genetics, ECLIPSE, and COPDGene Investigators
American journal of respiratory and critical care medicine · 2015 · PMID 26030696
3 pages
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations
Kowalski MH,
Qian H,
Hou Z,
Rosen JD,
Tapia AL,
Shan Y,
Jain D,
Argos M,
Arnett DK,
Avery C,
Barnes KC,
Becker LC
and 66 more — show all
Bien SA,
Bis JC,
Blangero J,
Boerwinkle E,
Bowden DW,
Buyske S,
Cai J,
Cho MH,
Choi SH,
Choquet H,
Cupples LA,
Cushman M,
Daya M,
de Vries PS,
Ellinor PT,
Faraday N,
Fornage M,
Gabriel S,
Ganesh SK,
Graff M,
Gupta N,
He J,
Heckbert SR,
Hidalgo B,
Hodonsky CJ,
Irvin MR,
Johnson AD,
Jorgenson E,
Kaplan R,
Kardia SLR,
Kelly TN,
Kooperberg C,
Lasky-Su JA,
Loos RJF,
Lubitz SA,
Mathias RA,
McHugh CP,
Montgomery C,
Moon JY,
Morrison AC,
Palmer ND,
Pankratz N,
Papanicolaou GJ,
Peralta JM,
Peyser PA,
Rich SS,
Rotter JI,
Silverman EK,
Smith JA,
Smith NL,
Taylor KD,
Thornton TA,
Tiwari HK,
Tracy RP,
Wang T,
Weiss ST,
Weng LC,
Wiggins KL,
Wilson JG,
Yanek LR,
Zöllner S,
North KE,
Auer PL,
Raffield LM,
Reiner AP,
Li Y
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium · TOPMed Hematology & Hemostasis Working Group
PLoS genetics · 2019 · PMID 31869403 · open access
3 pages
Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study
Manichaikul A,
Hoffman EA,
Smolonska J,
Gao W,
Cho MH,
Baumhauer H,
Budoff M,
Austin JH,
Washko GR,
Carr JJ,
Kaufman JD,
Pottinger T
and 22 more — show all
Powell CA,
Wijmenga C,
Zanen P,
Groen HJ,
Postma DS,
Wanner A,
Rouhani FN,
Brantly ML,
Powell R,
Smith BM,
Rabinowitz D,
Raffel LJ,
Hinckley Stukovsky KD,
Crapo JD,
Beaty TH,
Hokanson JE,
Silverman EK,
Dupuis J,
O'Connor GT,
Boezen HM,
Rich SS,
Barr RG
American journal of respiratory and critical care medicine · 2014 · PMID 24383474
2 pages
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis
Hobbs BD,
de Jong K,
Lamontagne M,
Bossé Y,
Shrine N,
Artigas MS,
Wain LV,
Hall IP,
Jackson VE,
Wyss AB,
London SJ,
North KE
and 64 more — show all
Franceschini N,
Strachan DP,
Beaty TH,
Hokanson JE,
Crapo JD,
Castaldi PJ,
Chase RP,
Bartz TM,
Heckbert SR,
Psaty BM,
Gharib SA,
Zanen P,
Lammers JW,
Oudkerk M,
Groen HJ,
Locantore N,
Tal-Singer R,
Rennard SI,
Vestbo J,
Timens W,
Paré PD,
Latourelle JC,
Dupuis J,
O'Connor GT,
Wilk JB,
Kim WJ,
Lee MK,
Oh YM,
Vonk JM,
de Koning HJ,
Leng S,
Belinsky SA,
Tesfaigzi Y,
Manichaikul A,
Wang XQ,
Rich SS,
Barr RG,
Sparrow D,
Litonjua AA,
Bakke P,
Gulsvik A,
Lahousse L,
Brusselle GG,
Stricker BH,
Uitterlinden AG,
Ampleford EJ,
Bleecker ER,
Woodruff PG,
Meyers DA,
Qiao D,
Lomas DA,
Yim JJ,
Kim DK,
Hawrylkiewicz I,
Sliwinski P,
Hardin M,
Fingerlin TE,
Schwartz DA,
Postma DS,
MacNee W,
Tobin MD,
Silverman EK,
Boezen HM,
Cho MH
COPDGene Investigators · ECLIPSE Investigators and 5 more consortia
Nature genetics · 2017 · PMID 28166215
2 pages
A genome-wide association study of pulmonary function measures in the Framingham Heart Study
Wilk JB,
Chen TH,
Gottlieb DJ,
Walter RE,
Nagle MW,
Brandler BJ,
Myers RH,
Borecki IB,
Silverman EK,
Weiss ST,
O'Connor GT
PLoS genetics · 2009 · PMID 19300500 · open access
1 page
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
Wilk JB,
Shrine NR,
Loehr LR,
Zhao JH,
Manichaikul A,
Lopez LM,
Smith AV,
Heckbert SR,
Smolonska J,
Tang W,
Loth DW,
Curjuric I
and 67 more — show all
Hui J,
Cho MH,
Latourelle JC,
Henry AP,
Aldrich M,
Bakke P,
Beaty TH,
Bentley AR,
Borecki IB,
Brusselle GG,
Burkart KM,
Chen TH,
Couper D,
Crapo JD,
Davies G,
Dupuis J,
Franceschini N,
Gulsvik A,
Hancock DB,
Harris TB,
Hofman A,
Imboden M,
James AL,
Khaw KT,
Lahousse L,
Launer LJ,
Litonjua A,
Liu Y,
Lohman KK,
Lomas DA,
Lumley T,
Marciante KD,
McArdle WL,
Meibohm B,
Morrison AC,
Musk AW,
Myers RH,
North KE,
Postma DS,
Psaty BM,
Rich SS,
Rivadeneira F,
Rochat T,
Rotter JI,
Soler Artigas M,
Starr JM,
Uitterlinden AG,
Wareham NJ,
Wijmenga C,
Zanen P,
Province MA,
Silverman EK,
Deary IJ,
Palmer LJ,
Cassano PA,
Gudnason V,
Barr RG,
Loos RJ,
Strachan DP,
London SJ,
Boezen HM,
Probst-Hensch N,
Gharib SA,
Hall IP,
O'Connor GT,
Tobin MD,
Stricker BH
American journal of respiratory and critical care medicine · 2012 · PMID 22837378
1 page
Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease
McDonald ML,
Cho MH,
Sørheim IC,
Lutz SM,
Castaldi PJ,
Lomas DA,
Coxson HO,
Edwards LD,
MacNee W,
Vestbo J,
Yates JC,
Agusti A
and 19 more — show all
Calverley PM,
Celli B,
Crim C,
Rennard SI,
Wouters EF,
Bakke P,
Tal-Singer R,
Miller BE,
Gulsvik A,
Casaburi R,
Wells JM,
Regan EA,
Make BJ,
Hokanson JE,
Lange C,
Crapo JD,
Beaty TH,
Silverman EK,
Hersh CP
Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints and COPDGene Investigators
American journal of respiratory cell and molecular biology · 2014 · PMID 24825563
1 page
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