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Self-reported childhood asthma in adult smokers

KIAA1958 · rs59289606

Where this position leads

Condition: Asthma

rs59289606 Condition: Asthma Asthma Condition rs59289606 rs59289606 KIAA1958

What the study found

Who was studied 385 European ancestry cases, 4979 European ancestry controls, 325 African American cases, 2342 African American controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 5 × 10−8.

How common The A allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 9, band 9q32 — in an intron of KIAA1958.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Self-reported childhood asthma in adult smokers compared to the general population.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Self-reported childhood asthma in adult smokers.
C/C Published research associates this genotype with typical/baseline likelihood of Self-reported childhood asthma in adult smokers — no copies of the reported risk allele.
Source

Questions about rs59289606

What is rs59289606?

rs59289606 is a single position in the genome, in or near the KIAA1958 gene. Published research associates it with self-reported childhood asthma in adult smokers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs59289606 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs59289606 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs59289606 come from?

GWAS Catalog, Respir Res 2018, PMID:30373671. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Self-reported childhood asthma in adult smokers (rs59289606). MyGeneLog™. https://www.mygenelog.com/variants/rs59289606

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