Sensitive

Chronic obstructive pulmonary disease in non-current smokers

LINC01807 · rs4973115

What the study found

Who was studied 16,488 European ancestry cases, 169,688 European ancestry controls.

The effect Each copy of the A allele carried 0.86 times the odds of Chronic obstructive pulmonary disease in non-current smokers (95% confidence interval 0.83-0.9); p = 5 × 10−10.

How common The A allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 2, band 2q36.3 — in an intron of LINC01807.

What each result means

A/A Two copies of the version the research linked to Chronic obstructive pulmonary disease in non-current smokers. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Chronic obstructive pulmonary disease in non-current smokers. That is a smaller link than two copies.
G/G No copy of the version the research linked to Chronic obstructive pulmonary disease in non-current smokers. This is the starting point the study compared everyone against.
Source

Questions about rs4973115

What is rs4973115?

rs4973115 is a single position in the genome, in or near the LINC01807 gene. Published research associates it with chronic obstructive pulmonary disease in non-current smokers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4973115 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4973115 come from?

GWAS Catalog, American journal of epidemiology 2021, PMID:33106845. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Chronic obstructive pulmonary disease in non-current smokers (rs4973115). MyGeneLog™. https://www.mygenelog.com/variants/rs4973115

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