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Hemoglobin levels

HBQ1 · rs11863726

What the study found

Who was studied 14,739 African American individuals, 6,762 African ancestry individuals, 21,686 Hispanic/Latino individuals; replicated in 7,037 African American individuals.

The effect Each copy of the G allele shifted the measure 0.104 lower; p = 6 × 10−24.

Where it sits Chromosome 16, band 16p13.3 — at a splice region of HBQ1.

What each result means

A/A No copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11863726

What is rs11863726?

rs11863726 is a single position in the genome, in or near the HBQ1 gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11863726 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11863726 come from?

GWAS Catalog, PLoS genetics 2019, PMID:31869403. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hemoglobin levels (rs11863726). MyGeneLog™. https://www.mygenelog.com/variants/rs11863726

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