Sensitive

Chronic obstructive pulmonary disease

CACNA2D3 · rs17759204

Where this position leads

Condition: Chronic Obstructive Pulmonary Disease (COPD)

rs17759204 Condition: Chronic Obstructive Pulmonary Disease (COPD) Chronic Obstructive Pulmonary Disea… Condition rs17759204 rs17759204 CACNA2D3

What the study found

Who was studied 35,735 cases, 222,076 controls.

The effect Each copy of the G allele carried 1.07 times the odds of Chronic obstructive pulmonary disease (95% confidence interval 1.05-1.10); p = 9 × 10−11.

How common The G allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 3, band 3p14.3 — between genes, 49.6 kb from CACNA2D3.

What each result means

A/A No copy of the version the research linked to Chronic obstructive pulmonary disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Chronic obstructive pulmonary disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Chronic obstructive pulmonary disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17759204

What is rs17759204?

rs17759204 is a single position in the genome, in or near the CACNA2D3 gene. Published research associates it with chronic obstructive pulmonary disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17759204 linked to?

On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.

Does having rs17759204 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17759204 come from?

GWAS Catalog, Nature genetics 2019, PMID:30804561. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Chronic obstructive pulmonary disease (rs17759204). MyGeneLog™. https://www.mygenelog.com/variants/rs17759204

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