Chronic obstructive pulmonary disease in non-current smokers
near FGF18 · rs12519165
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 16,488 European ancestry cases, 169,688 European ancestry controls.
The effect
Each copy of the A allele carried 1.08 times the odds of Chronic obstructive pulmonary disease in non-current smokers (95% confidence interval 1.06-1.11); p = 6 × 10−10.
How common The A allele had a frequency of about 39% in the people studied.
Where it sits Chromosome 5, band 5q35.1 — between genes, 17 kb from FGF18.
What each result means
A/ATwo copies of the version the research linked to Chronic obstructive pulmonary disease in non-current smokers. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Chronic obstructive pulmonary disease in non-current smokers. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Chronic obstructive pulmonary disease in non-current smokers. This is the starting point the study compared everyone against.
American journal of epidemiology · 2021 · PMID 33106845
Questions about rs12519165
What is rs12519165?
rs12519165 is a single position in the genome, in or near the near FGF18 gene. Published research associates it with chronic obstructive pulmonary disease in non-current smokers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs12519165 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12519165 come from?
GWAS Catalog, American journal of epidemiology 2021, PMID:33106845. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Chronic obstructive pulmonary disease in non-current smokers (rs12519165). MyGeneLog™. https://www.mygenelog.com/variants/rs12519165