AGPHD1 · rs11852372
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,732 European ancestry smoker individuals, 2,724 European ancestry chronic obstructive pulmonary disease smoker cases, 2,372 African American smoker individuals, 786 African American chronic obstructive pulmonary disease smoker cases.
The effect Each copy of the A allele shifted the measure 0.003 lower (95% confidence interval 0.0018-0.0042); p = 1 × 10−7.
How common The A allele had a frequency of about 65% in the people studied.
Where it sits Chromosome 15, band 15q25.1 — in an intron of HYKK.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs11852372 is a single position in the genome, in or near the AGPHD1 gene. Published research associates it with local histogram emphysema pattern. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Am J Respir Crit Care Med 2014, PMID:25006744. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Local histogram emphysema pattern (rs11852372). MyGeneLog™. https://www.mygenelog.com/variants/rs11852372