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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals.
The effect
Each copy of the A allele shifted the measure 0.019 lower; p = 4 × 10−10.
How common The A allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 11, band 11q22.2 — between genes, 7.3 kb from MMP12.
What each result means
A/ATwo copies of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. This is the starting point the study compared everyone against.
rs737693 is a single position in the genome, in or near the near MMP12 gene. Published research associates it with post bronchodilator fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs737693 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs737693 come from?
GWAS Catalog, BMC genetics 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Post bronchodilator FEV1/FVC ratio (rs737693). MyGeneLog™. https://www.mygenelog.com/variants/rs737693