C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Chronic obstructive pulmonary disease (severe) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Chronic obstructive pulmonary disease (severe).
T/TPublished research associates this genotype with typical/baseline likelihood of Chronic obstructive pulmonary disease (severe) — no copies of the reported risk allele.
The Lancet. Respiratory medicine · 2014 · PMID 24621683
Questions about rs4416442
What is rs4416442?
rs4416442 is a single position in the genome, in or near the FAM13A gene. Published research associates it with chronic obstructive pulmonary disease (severe). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4416442 linked to?
On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.
Does having rs4416442 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4416442 come from?
GWAS Catalog, Lancet Respir Med 2014, PMID:24621683. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.