HHIP · rs13147758
Where this position leads
Condition: Pulmonary Function (Lung Capacity)
What the study found
Who was studied 7,691 European ancestry individuals; replicated in 835 European ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.1 % higher; p = 8 × 10−11.
How common The G allele had a frequency of about 39% in the people studied.
Where it sits Chromosome 4, band 4q31.21 — in an intron of LOC105377462.
What ClinVar records
Classification
association for Chronic obstructive pulmonary disease, Chronic obstructive pulmonary disease, biomass related; no assertion criteria provided (0 of 4 stars, 1 submitter), last evaluated 2020-02-12.
ClinVar record 870129 NC_000004.12:g.144539078A>G
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs13147758 is a single position in the genome, in or near the HHIP gene. Published research associates it with pulmonary function. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS Genet 2009, PMID:19300500. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Pulmonary function (rs13147758). MyGeneLog™. https://www.mygenelog.com/variants/rs13147758