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Emphysema distribution in smoking

CHRNA3 · rs138544659

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Emphysema distribution in smoking — no copies of the reported risk allele. (GWAS Catalog, Am J Respir Crit Care Med 2016, PMID:27669027)

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Emphysema distribution in smoking. (GWAS Catalog, Am J Respir Crit Care Med 2016, PMID:27669027)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Emphysema distribution in smoking compared to the general population. (GWAS Catalog, Am J Respir Crit Care Med 2016, PMID:27669027)

Source: GWAS Catalog, Am J Respir Crit Care Med 2016, PMID:27669027

Questions about rs138544659

What is rs138544659?

rs138544659 is a single position in the genome, in or near the CHRNA3 gene. Published research associates it with emphysema distribution in smoking. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs138544659 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138544659 come from?

GWAS Catalog, Am J Respir Crit Care Med 2016, PMID:27669027. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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