Standard
Emphysema distribution in smoking
KIAA1462 · rs35374984
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Emphysema distribution in smoking compared to the general population.
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Emphysema distribution in smoking.
C/C
Published research associates this genotype with typical/baseline likelihood of Emphysema distribution in smoking — no copies of the reported risk allele.
Source
Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution
Boueiz A,
Lutz SM,
Cho MH,
Hersh CP,
Bowler RP,
Washko GR,
Halper-Stromberg E,
Bakke P,
Gulsvik A,
Laird NM,
Beaty TH,
Coxson HO
and 4 more — show all
American journal of respiratory and critical care medicine · 2017 · PMID 27669027
Questions about rs35374984
What is rs35374984?
rs35374984 is a single position in the genome, in or near the KIAA1462 gene. Published research associates it with emphysema distribution in smoking. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs35374984 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs35374984 come from?
GWAS Catalog, Am J Respir Crit Care Med 2016, PMID:27669027. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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