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The effect
Each copy of the C allele carried 1.12 times the odds of Chronic obstructive pulmonary disease; p = 5 × 10−11.
How common The C allele had a frequency of about 90% in the people studied.
Where it sits Chromosome 15, band 15q25.2 — in an intron of ADAMTSL3.
What each result means
C/CTwo copies of the version the research linked to Chronic obstructive pulmonary disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Chronic obstructive pulmonary disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Chronic obstructive pulmonary disease. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30804561 · open access
Questions about rs4523894
What is rs4523894?
rs4523894 is a single position in the genome, in or near the ADAMTSL3 gene. Published research associates it with chronic obstructive pulmonary disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4523894 linked to?
On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.
Does having rs4523894 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4523894 come from?
GWAS Catalog, Nature genetics 2019, PMID:30804561. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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