Standard

Post bronchodilator FEV1/FVC ratio

CHRNA5 · rs72740964

Where this position leads

Condition: Chronic Obstructive Pulmonary Disease (COPD)

rs72740964 Condition: Chronic Obstructive Pulmonary Disease (COPD) Chronic Obstructive Pulmonary Disea… Condition rs72740964 rs72740964 CHRNA5

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Post bronchodilator FEV1/FVC ratio compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Post bronchodilator FEV1/FVC ratio.
G/G Published research associates this genotype with typical/baseline likelihood of Post bronchodilator FEV1/FVC ratio — no copies of the reported risk allele.
Source

Questions about rs72740964

What is rs72740964?

rs72740964 is a single position in the genome, in or near the CHRNA5 gene. Published research associates it with post bronchodilator fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72740964 linked to?

On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.

Does having rs72740964 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72740964 come from?

GWAS Catalog, BMC Genet 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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